Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
about
Extending healthy life span--from yeast to humansmTOR is a key modulator of ageing and age-related diseaseChemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processesReplicative and chronological aging in Saccharomyces cerevisiae.Extreme-longevity mutations orchestrate silencing of multiple signaling pathwaysThe Epigenetic Pathways to Ribosomal DNA SilencingDietary restriction with and without caloric restriction for healthy agingDietary Restriction and Nutrient Balance in AgingDysregulated metabolism contributes to oncogenesisThe metabolism beyond programmed cell death in yeastAging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicansThe TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast developmentA yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily.Yeast histone H3 lysine 4 demethylase Jhd2 regulates mitotic rDNA condensationGenome-wide screen in Saccharomyces cerevisiae identifies vacuolar protein sorting, autophagy, biosynthetic, and tRNA methylation genes involved in life span regulation.Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phaseCharacterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathwayPotential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disordersBetter Living through Chemistry: Caloric Restriction (CR) and CR Mimetics Alter Genome Function to Promote Increased Health and LifespanMethionine restriction and life-span controlSlm35 links mitochondrial stress response and longevity through TOR signaling pathwayA yeast-based genomic strategy highlights the cell protein networks altered by FTase inhibitor peptidomimeticsDown-regulating sphingolipid synthesis increases yeast lifespanEvolution of human longevity uncoupled from caloric restriction mechanismsSimilar environments but diverse fates: Responses of budding yeast to nutrient deprivationThe histone demethylase activity of Rph1 is not essential for its role in the transcriptional response to nutrient signalingSix plant extracts delay yeast chronological aging through different signaling pathwaysDiscovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processesYeast sirtuins and the regulation of aging.Combinatorial control of gene expression by the three yeast repressors Mig1, Mig2 and Mig3Pro-aging effects of glucose signaling through a G protein-coupled glucose receptor in fission yeast.Environmental and genetic determinants of colony morphology in yeastFasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy LifespanComparative analyses of time-course gene expression profiles of the long-lived sch9Delta mutant.Growth and aging: a common molecular mechanism.Methionine restriction activates the retrograde response and confers both stress tolerance and lifespan extension to yeast, mouse and human cellsCalorie restriction in mammals and simple model organisms.Calorie restriction and cancer prevention: metabolic and molecular mechanisms.
P2860
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P2860
Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@ast
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en-gb
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@nl
type
label
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@ast
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en-gb
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@nl
altLabel
Life Span Extension by Calorie ...... ream of Ras/PKA, Tor, and Sch9
@en
prefLabel
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@ast
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en-gb
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@nl
P2093
P2860
P3181
P1433
P1476
Life span extension by calorie ...... ream of Ras/PKA, Tor, and Sch9
@en
P2093
Chao Cheng
Huanying Ge
Paola Fabrizio
Valter D Longo
P2860
P3181
P356
10.1371/JOURNAL.PGEN.0040013
P407
P577
2008-01-01T00:00:00Z