CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses. - Test2 - elhamkhani - TriplyDB

CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.

CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.

http://www.wikidata.org/entity/Q33826217

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Cenh3: An Emerging Player in Haploid Induction Technology An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone H3 variant via the centromere targeting domain SUMO-Targeted Ubiquitin Ligase (STUbL) Slx5 regulates proteolysis of centromeric histone H3 variant Cse4 and prevents its mislocalization to euchromatin.ShRNA-targeted centromere protein A inhibits hepatocellular carcinoma growth Modulation of HJURP (Holliday Junction-Recognizing Protein) levels is correlated with glioblastoma cells survival Higher-order unfolding of satellite heterochromatin is a consistent and early event in cell senescence Essential role for centromeric factors following p53 loss and oncogenic transformation Centromere protein A dynamics in human pluripotent stem cell self-renewal, differentiation and DNA damage.The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes.Integrity of the human centromere DNA repeats is protected by CENP-A, CENP-C, and CENP-T.The transcriptional cofactor MCAF1/ATF7IP is involved in histone gene expression and cellular senescence Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas.Generating a transgenic mouse line stably expressing human MHC surface antigen from a HAC carrying multiple genomic BACs.Centromeric chromatin and the pathway that drives its propagation.Regulation of Budding Yeast CENP-A levels Prevents Misincorporation at Promoter Nucleosomes and Transcriptional Defects.Unfolding the story of chromatin organization in senescent cells.Potential roles of DNA methylation in the initiation and establishment of replicative senescence revealed by array-based methylome and transcriptome analyses.Whole chromosome aneuploidy in the brain of Bub1bH/H and Ercc1-/Δ7 mice.DNA deletion as a mechanism for developmentally programmed centromere loss.Lessons from senescence: Chromatin maintenance in non-proliferating cells.Brassica juncea Lines with Substituted Chimeric GFP-CENH3 Give Haploid and Aneuploid Progenies on Crossing with Other Lines.CENP-A is essential for cardiac progenitor cell proliferation.Chromatin dynamics: H3K4 methylation and H3 variant replacement during development and in cancer.Chromatin maintenance and dynamics in senescence: a spotlight on SAHF formation and the epigenome of senescent cells.Genetic and epigenetic regulation of centromeres: a look at HAC formation.Living in CIN: Mitotic Infidelity and Its Consequences for Tumor Promotion and Suppression.Mitotic centromere-associated kinase (MCAK/Kif2C) regulates cellular senescence in human primary cells through a p53-dependent pathway.Concise Review: Challenges in Regenerating the Diabetic Heart: A Comprehensive Review.Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth.The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program.A PSHaver for centromeric histones.CENP-A chromatin disassembly in stressed and senescent murine cells.Knockdown of CENH3 in Arabidopsis reduces mitotic divisions and causes sterility by disturbed meiotic chromosome segregation.Human Centromeres Produce Chromosome-Specific and Array-Specific Alpha Satellite Transcripts that Are Complexed with CENP-A and CENP-C.Stathmin/Op18 depletion induces genomic instability and leads to premature senescence in human normal fibroblasts.Short hairpin RNA-mediated down-regulation of CENP-A attenuates the aggressive phenotype of lung adenocarcinoma cells.HJURP regulates cellular senescence in human fibroblasts and endothelial cells via a p53-dependent pathway.Down-regulation of Aurora B kinase induces cellular senescence in human fibroblasts and endothelial cells through a p53-dependent pathway.E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53.The dark side of centromeres: types, causes and consequences of structural abnormalities implicating centromeric DNA

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P2860

CENP-A reduction induces a p53-dependent cellular senescence response to protect cells from executing defective mitoses.

http://www.wikidata.org/entity/Q33826217

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

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2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

@wuu

name

CENP-A reduction induces a p53 ...... m executing defective mitoses.

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CENP-A reduction induces a p53 ...... m executing defective mitoses.

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CENP-A reduction induces a p53 ...... m executing defective mitoses.

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CENP-A reduction induces a p53 ...... m executing defective mitoses.

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CENP-A reduction induces a p53 ...... m executing defective mitoses.

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CENP-A reduction induces a p53 ...... m executing defective mitoses.

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Molecular and Cellular Biology

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CENP-A reduction induces a p53 ...... m executing defective mitoses.

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Kayoko Maehara

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Kohta Takahashi

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Shigeaki Saitoh

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P2860

A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway

Chromatin association of human origin recognition complex, cdc6, and minichromosome maintenance proteins during the cell cycle: assembly of prereplication complexes in late mitosis

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

Epstein-Barr virus LMP1 blocks p16INK4a-RB pathway by promoting nuclear export of E2F4/5

Assembly of CENP-A into centromeric chromatin requires a cooperative array of nucleosomal DNA contact sites

High-efficiency transformation of mammalian cells by plasmid DNA

The spindle-assembly checkpoint in space and time

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2090-2104

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10.1128/MCB.01318-09

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9

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30

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2010-02-16T00:00:00Z

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20160010

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2863584

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