Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
about
Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4)Systems Pharmacology in Small Molecular Drug DiscoveryTarget prediction utilising negative bioactivity data covering large chemical spaceA combination of metabolic labeling and 2D-DIGE analysis in response to a farnesyltransferase inhibitor facilitates the discovery of new prenylated proteins.Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferationThe chemical basis of pharmacology.Non-bisphosphonate inhibitors of isoprenoid biosynthesis identified via computer-aided drug design.An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthasesSmall molecule inhibitors of Smoothened ciliary localization and ciliogenesisActivity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic InferenceExploring the ligand-protein networks in traditional chinese medicine: current databases, methods, and applicationsAndrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function.Design and synthesis of some new 2,3'-bipyridine-5-carbonitriles as potential anti-inflammatory/antimicrobial agents.Rare Diseases: Drug Discovery and Informatics Resource.A Simple Representation of Three-Dimensional Molecular Structure.Predicted Biological Activity of Purchasable Chemical Space.Mapping of pharmacological space.On the origins of drug polypharmacology
P2860
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P2860
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
@ast
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
@en
type
label
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
@ast
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
@en
prefLabel
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
@ast
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs.
@en
P2093
P2860
P356
P1476
Prediction and evaluation of protein farnesyltransferase inhibition by commercial drugs
@en
P2093
Amanda J DeGraw
Brian K Shoichet
Joshua D Ochocki
Mark D Distefano
P2860
P304
P356
10.1021/JM901613F
P407
P577
2010-03-01T00:00:00Z