Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles - Test2 - elhamkhani - TriplyDB

Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles

Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles

http://www.wikidata.org/entity/Q33841491

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Kinesin-5: cross-bridging mechanism to targeted clinical therapy The chromokinesin Kid is required for maintenance of proper metaphase spindle size.Towards a quantitative understanding of mitotic spindle assembly and mechanics The 3Ms of central spindle assembly: microtubules, motors and MAPs An organelle-exclusion envelope assists mitosis and underlies distinct molecular crowding in the spindle region KLP-7 acts through the Ndc80 complex to limit pole number in C. elegans oocyte meiotic spindle assembly.Lateral microtubule bundles promote chromosome alignment during acentrosomal oocyte meiosis Self-organization of stabilized microtubules by both spindle and midzone mechanisms in Xenopus egg cytosol.Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis.Microtubules can bear enhanced compressive loads in living cells because of lateral reinforcement.Myosin-10 and actin filaments are essential for mitotic spindle function Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle.Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules Mechanical impulses can control metaphase progression in a mammalian cell Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation.Development of a Drosophila cell-based error correction assay.Kinesin-12 differentially affects spindle assembly depending on its microtubule substrate Kinetochore-microtubule stability governs the metaphase requirement for Eg5.Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion.A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes.Physical determinants of bipolar mitotic spindle assembly and stability in fission yeast.A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.Directly probing the mechanical properties of the spindle and its matrix.Kinesin-5-independent mitotic spindle assembly requires the antiparallel microtubule crosslinker Ase1 in fission yeast A membranous spindle matrix orchestrates cell division.RNA stimulates Aurora B kinase activity during mitosis.Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14 Actomyosin-dependent cortical dynamics contributes to the prophase force-balance in the early Drosophila embryo Using micromanipulation to analyze control of vertebrate meiotic spindle size MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment.Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK.The role of actin and myosin in PtK2 spindle length changes induced by laser microbeam irradiations across the spindle.Measurements of forces produced by the mitotic spindle using optical tweezers Insights into the micromechanical properties of the metaphase spindle p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation.NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules.Spindle pole mechanics studied in mitotic asters: dynamic distribution of spindle forces through compliant linkages.Microtubule assembly in meiotic extract requires glycogen.Mechanical design principles of a mitotic spindle Movement of chromosomes with severed kinetochore microtubules.

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Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles

http://www.wikidata.org/entity/Q33841491

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Molecular Biology of the Cell

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Roles of polymerization dynami ...... nopus extract meiotic spindles

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A Groen

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E D Salmon

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P2860

Opposing motor activities are required for the organization of the mammalian mitotic spindle pole

Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.

Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles.

The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement

Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

Mitotic spindle organization by a plus-end-directed microtubule motor

Control of microtubule dynamics by the antagonistic activities of XMAP215 and XKCM1 in Xenopus egg extracts.

Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations.

Regulation of the in vivo mitotic apparatus by glycols and metabolic inhibitors.

Microtubule motors in mitosis.

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15788560

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