DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge. - Test2 - elhamkhani - TriplyDB

DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge.

DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge.

http://www.wikidata.org/entity/Q33843297

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Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2 Can immunotherapy be useful as a "functional cure" for infection with Human Immunodeficiency Virus-1?DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques Willingness to participate in HIV therapeutic vaccine trials among HIV-infected patients on ART in China A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.Combined administration with DNA encoding vesicular stomatitis virus G protein enhances DNA vaccine potency Repeated DNA therapeutic vaccination of chronically SIV-infected macaques provides additional virological benefit Vaccination with Gag, Vif, and Nef gene fragments affords partial control of viral replication after mucosal challenge with SIVmac239 Virion envelope content, infectivity, and neutralization sensitivity of simian immunodeficiency virus.Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques.Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection The influence of delivery vectors on HIV vaccine efficacy Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.Fundamental difference in the content of high-mannose carbohydrate in the HIV-1 and HIV-2 lineages.A novel, live-attenuated vesicular stomatitis virus vector displaying conformationally intact, functional HIV-1 envelope trimers that elicits potent cellular and humoral responses in mice.DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.Simian immunodeficiency virus from the sooty mangabey and rhesus macaque is modified with O-linked carbohydrate.Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers Comparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaques HIV-1 p24(gag) derived conserved element DNA vaccine increases the breadth of immune response in mice.Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cells.Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques Enhanced control of pathogenic Simian immunodeficiency virus SIVmac239 replication in macaques immunized with an interleukin-12 plasmid and a DNA prime-viral vector boost vaccine regimen.DNA/Ad5 vaccination with SIV epitopes induced epitope-specific CD4⁺ T cells, but few subdominant epitope-specific CD8⁺ T cells Long-lasting decrease in viremia in macaques chronically infected with simian immunodeficiency virus SIVmac251 after therapeutic DNA immunization Vaccine induced antibodies to the first variable loop of human immunodeficiency virus type 1 gp120, mediate antibody-dependent virus inhibition in macaques.Evidence against extracellular exposure of a highly immunogenic region in the C-terminal domain of the simian immunodeficiency virus gp41 transmembrane protein TLR agonists and/or IL-15 adjuvanted mucosal SIV vaccine reduced gut CD4⁺ memory T cell loss in SIVmac251-challenged rhesus macaques.Ability of herpes simplex virus vectors to boost immune responses to DNA vectors and to protect against challenge by simian immunodeficiency virus The cytoplasmic domain of the HIV-1 glycoprotein gp41 induces NF-κB activation through TGF-β-activated kinase 1.HIV DNA Vaccine: Stepwise Improvements Make a Difference.Regulation of Immunogen Processing: Signal Sequences and Their Application for the New Generation of DNA-Vaccines Lessons in nonhuman primate models for AIDS vaccine research: from minefields to milestones.New paradigms for HIV/AIDS vaccine development.Vaccine-Induced Simian Immunodeficiency Virus-Specific CD8+ T-Cell Responses Focused on a Single Nef Epitope Select for Escape Variants Shortly after Infection.Dose-dependent inhibition of Gag cellular immunity by Env in SIV/HIV DNA vaccinated macaques DNA is an efficient booster of dendritic cell-based vaccine DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge The p40 subunit of interleukin (IL)-12 promotes stabilization and export of the p35 subunit: implications for improved IL-12 cytokine production.

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P2860

DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge.

http://www.wikidata.org/entity/Q33843297

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2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

DNA vaccines expressing differ ...... emia upon SIVmac251 challenge.

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DNA vaccines expressing differ ...... emia upon SIVmac251 challenge.

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DNA vaccines expressing differ ...... emia upon SIVmac251 challenge.

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DNA vaccines expressing differ ...... emia upon SIVmac251 challenge.

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JVI.79.13.8480-8492.2005

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Journal of Virology

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DNA vaccines expressing differ ...... emia upon SIVmac251 challenge.

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Agneta von Gegerfelt

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Antonio Valentin

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Barbara K Felber

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Candido Alicea

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David Venzon

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George N Pavlakis

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Margherita Rosati

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Marjorie Robert-Guroff

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Patricia Roth

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Phil Markham

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P2860

DNA vaccines: immunology, application, and optimization*

More powerful procedures for multiple significance testing

beta-catenin is a target for the ubiquitin-proteasome pathway

The moving target: mechanisms of HIV persistence during primary infection.

Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection.

Evaluation of novel human immunodeficiency virus type 1 Gag DNA vaccines for protein expression in mammalian cells and induction of immune responses.

Genetic adjuvants for DNA vaccines.

Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.

Novel engineered HIV-1 East African Clade-A gp160 plasmid construct induces strong humoral and cell-mediated immune responses in vivo.

The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region.

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8480-8492

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10.1128/JVI.79.13.8480-8492.2005

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13

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David C Montefiori

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7785448

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Simian immunodeficiency virus

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