Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization. - Test2 - elhamkhani - TriplyDB

Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.

Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.

http://www.wikidata.org/entity/Q34099837

about

DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques Long-term central and effector SHIV-specific memory T cell responses elicited after a single immunization with a novel lentivector DNA vaccine Immunogenicity of DNA vaccines encoding simian immunodeficiency virus antigen targeted to dendritic cells in rhesus macaques Controlling the HIV/AIDS epidemic: current status and global challenges Human immunodeficiency virus vaccine trials A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques.Altered response hierarchy and increased T-cell breadth upon HIV-1 conserved element DNA vaccination in macaques.Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities Induction of neutralizing antibody response against four dengue viruses in mice by intramuscular electroporation of tetravalent DNA vaccines.Humoral immunity induced by mucosal and/or systemic SIV-specific vaccine platforms suggests novel combinatorial approaches for enhancing responses.The influence of delivery vectors on HIV vaccine efficacy DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.Kinetic and phenotypic analysis of CD8+ T cell responses after priming with alphavirus replicons and homologous or heterologous booster immunizations Comparative analysis of SIV-specific cellular immune responses induced by different vaccine platforms in rhesus macaques Comparison of immune responses generated by optimized DNA vaccination against SIV antigens in mice and macaques Diverse peptide presentation of rhesus macaque major histocompatibility complex class I Mamu-A 02 revealed by two peptide complex structures and insights into immune escape of simian immunodeficiency virus.HIV DNA Vaccine: Stepwise Improvements Make a Difference.Optimized in vivo transfer of small interfering RNA targeting dermal tissue using in vivo surface electroporation.DNA is an efficient booster of dendritic cell-based vaccine Plasmid DNA Vaccine Co-Immunisation Modulates Cellular and Humoral Immune Responses Induced by Intranasal Inoculation in Mice.DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1.IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques A novel SIV gag-specific CD4(+)T-cell clone suppresses SIVmac239 replication in CD4(+)T cells revealing the interplay between antiviral effector cells and their infected targets Induction of mucosal immunity through systemic immunization: Phantom or reality?DNA Prime-Boost Vaccine Regimen To Increase Breadth, Magnitude, and Cytotoxicity of the Cellular Immune Responses to Subdominant Gag Epitopes of Simian Immunodeficiency Virus and HIV.Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses.Vaccination with Vaxfectin(®) adjuvanted SIV DNA induces long-lasting humoral immune responses able to reduce SIVmac251 Viremia.Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.Prime-boost immunization with poxvirus or adenovirus vectors as a strategy to develop a protective vaccine for HIV-1.Revival of the identification of cytotoxic T-lymphocyte epitopes for immunological diagnosis, therapy and vaccine development.Differential T-cell responses to a chimeric Plasmodium falciparum antigen; UB05-09, correlates with acquired immunity to malaria.Codon-Optimized P1A-Encoding DNA Vaccine: Toward a Therapeutic Vaccination against P815 Mastocytoma Lack of IL-7 and IL-15 signaling affects interferon-γ production by, more than survival of, small intestinal intraepithelial memory CD8+ T cells.Control of Heterologous Simian Immunodeficiency Virus SIV Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques

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P2860

Long-lasting humoral and cellular immune responses and mucosal dissemination after intramuscular DNA immunization.

http://www.wikidata.org/entity/Q34099837

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Long-lasting humoral and cellu ...... ntramuscular DNA immunization.

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J.VACCINE.2010.04.064

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Long-lasting humoral and cellu ...... ntramuscular DNA immunization.

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P2093

Amir S Khan

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Antonio Valentin

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Barbara K Felber

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Candido Alicea

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Claes Ohlen

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Cristina Bergamaschi

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George N Pavlakis

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Jacob T Minang

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Jun Zhao

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Margherita Rosati

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P2860

IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine

Distribution, persistence, and efficacy of adoptively transferred central and effector memory-derived autologous simian immunodeficiency virus-specific CD8+ T cell clones in rhesus macaques during acute infection.

Effective induction of simian immunodeficiency virus-specific systemic and mucosal immune responses in primates by vaccination with proviral DNA producing intact but noninfectious virions

Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection.

DNA vaccines expressing different forms of simian immunodeficiency virus antigens decrease viremia upon SIVmac251 challenge.

Increased DNA vaccine delivery and immunogenicity by electroporation in vivo.

Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine.

Both mucosal and systemic routes of immunization with the live, attenuated NYVAC/simian immunodeficiency virus SIV(gpe) recombinant vaccine result in gag-specific CD8(+) T-cell responses in mucosal tissues of macaques.

P304

4827-4836

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10.1016/J.VACCINE.2010.04.064

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30

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