Current status on Alzheimer disease molecular genetics: from past, to present, to future.
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Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's diseaseInteractome mapping suggests new mechanistic details underlying Alzheimer's diseaseSynapses and Alzheimer's diseaseAmyloid-beta Alzheimer targets - protein processing, lipid rafts, and amyloid-beta poresPhysiological and pathological phosphorylation of tau by Cdk5The E2 Domains of APP and APLP1 Share a Conserved Mode of DimerizationCrystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerizationAnti-aggregating effect of the naturally occurring dipeptide carnosine on aβ1-42 fibril formationAmyloid oligomer neurotoxicity, calcium dysregulation, and lipid raftsOverrepresentation of glutamate signaling in Alzheimer's disease: network-based pathway enrichment using meta-analysis of genome-wide association studies.Drug development status for Alzheimer's disease: present scenario.Genetics of dementia.Pharmacodynamic, pharmacokinetic and pharmacogenetic aspects of drugs used in the treatment of Alzheimer's disease.A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease.Adaptors for disorders of the brain? The cancer signaling proteins NEDD9, CASS4, and PTK2B in Alzheimer's disease.HMGCR is a genetic modifier for risk, age of onset and MCI conversion to Alzheimer's disease in a three cohorts study.Genetic Association between Akt1 Polymorphisms and Alzheimer's Disease in a Japanese PopulationCLOCK Genes and Circadian Rhythmicity in Alzheimer Disease.Drug development for Alzheimer's disease: recent progressStructural and mechanistic commonalities of amyloid-β and the prion proteinDiscovering Alzheimer Genetic Biomarkers Using Bayesian Networks.Amyloid deposition and advanced age fails to induce Alzheimer's type progression in a double knock-in mouse modelNo Associations Found between PGBD1 and the Age of Onset in Japanese Patients Diagnosed with Sporadic Alzheimer's DiseaseDevelopmental regulation of expression of schizophrenia susceptibility genes in the primate hippocampal formation.Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD miceGenetic Association between Neurotrophin-3 Polymorphisms and Alzheimer's Disease in Japanese PatientsIntegrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer's disease.Novel drug targets based on metallobiology of Alzheimer's disease.Genetics of Alzheimer's disease: an insight into presenilins and apolipoprotein E instigated neurodegeneration.Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges.Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: a systematic review and meta-analysis.Lessons from genome-wide association studies findings in Alzheimer's disease.The potential role of rho GTPases in Alzheimer's disease pathogenesis.Research and development of anti-Alzheimer's drugs: an analysis based on technology flows measured by patent citations.Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progressionPhenotypic screening with primary neurons to identify drug targets for regeneration and degeneration.The relationship between amyloid deposition, neurodegeneration, and cognitive decline in dementia.Expression of the newly identified gene CAC1 in the hippocampus of Alzheimer's disease patients.Is AD a homogeneous nosologic entity? Yes.Association between EXOC3L2 rs597668 polymorphism and Alzheimer's disease.
P2860
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P2860
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
description
2010 nî lūn-bûn
@nan
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@ast
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@en
type
label
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@ast
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@en
prefLabel
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@ast
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@en
P2860
P356
P1476
Current status on Alzheimer disease molecular genetics: from past, to present, to future.
@en
P2093
Karolien Bettens
P2860
P304
P356
10.1093/HMG/DDQ142
P5008
P577
2010-04-13T00:00:00Z
2010-04-15T00:00:00Z