The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease - Test2 - elhamkhani - TriplyDB

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

http://www.wikidata.org/entity/Q24656574

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KIBRA: A New Gateway to Learning and Memory?The diploid genome sequence of an Asian individual The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid.Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease SORL1 variants and risk of late-onset Alzheimer's disease Quantitative modelling of amyloidogenic processing and its influence by SORLA in Alzheimer's disease SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1 The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation Deficiency of sorting nexin 27 (SNX27) leads to growth retardation and elevated levels of N-methyl-D-aspartate receptor 2C (NR2C)Lessons from epidemiologic research about risk factors, modifiers, and progression of late onset Alzheimer's Disease in New York City at Columbia University Medical Center Genetic aspects of Alzheimer disease Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy Apolipoprotein E receptors in the nervous system Assessment of Alzheimer's disease case-control associations using family-based methods Genetics of late-onset Alzheimer's disease: update from the alzgene database and analysis of shared pathways A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease Diagnosis and treatment of dementia: 1. Risk assessment and primary prevention of Alzheimer disease Lipoprotein receptors and cholesterol in APP trafficking and proteolytic processing, implications for Alzheimer's disease Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation Endophenotypes in normal brain morphology and Alzheimer's disease: a review Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 Loss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin Long noncoding RNAs and Alzheimer's disease Genes associated with Alzheimer's disease: an overview and current status The amyloid hypothesis of Alzheimer's disease at 25 years Role of the Retromer Complex in Neurodegenerative Diseases Genetic and Transcriptomic Profiles of Inflammation in Neurodegenerative Diseases: Alzheimer, Parkinson, Creutzfeldt-Jakob and Tauopathies Alzheimer's Disease: Mechanism and Approach to Cell Therapy The genetic landscape of Alzheimer disease: clinical implications and perspectives Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers Trafficking regulation of proteins in Alzheimer's disease The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer's disease Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease

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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease

http://www.wikidata.org/entity/Q24656574

description

2007 nî lūn-bûn

@nan

2007 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

The neuronal sortilin-related ...... ociated with Alzheimer disease

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The neuronal sortilin-related ...... ociated with Alzheimer disease

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The neuronal sortilin-related ...... ociated with Alzheimer disease

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type

label

The neuronal sortilin-related ...... ociated with Alzheimer disease

@ast

The neuronal sortilin-related ...... ociated with Alzheimer disease

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The neuronal sortilin-related ...... ociated with Alzheimer disease

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prefLabel

The neuronal sortilin-related ...... ociated with Alzheimer disease

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The neuronal sortilin-related ...... ociated with Alzheimer disease

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The neuronal sortilin-related ...... ociated with Alzheimer disease

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Nature Genetics

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The neuronal sortilin-related ...... ociated with Alzheimer disease

@en

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Amalia Bruni

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Christopher Bohm

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Fanggeng Zou

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Fusheng Chen

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Hideaki Bujo

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Hiroshi Hasegawa

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Innocenzo Rainero

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Karen T Cuenco

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L Adrienne Cupples

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Lorenzo Pinessi

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P2860

The allelic architecture of human disease genes: common disease-common variant... or not?

Are rare variants responsible for susceptibility to complex diseases?

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.

Pathways towards and away from Alzheimer's disease

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

Schizophrenia: genes at last?

Loss of apolipoprotein E receptor LR11 in Alzheimer disease

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10.1038/NG1943

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2

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39

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Ekaterina Rogaeva

Gerold Schmitt-Ulms

Dennis W. Dickson

Olav M. Andersen

Clinton Baldwin

Lindsay A. Farrer

Kathryn L. Lunetta

Thomas E Willnow

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2007-02-01T00:00:00Z

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6580696

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1004831996

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17220890

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Alzheimer's disease

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2657343

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