Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias. - Test2 - elhamkhani - TriplyDB

Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

http://www.wikidata.org/entity/Q33897191

about

Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm Expression of stabilized beta-catenin in differentiated neurons of transgenic mice does not result in tumor formation.Beta-catenin: a transforming actor on many stages Proteotypic classification of spontaneous and transgenic mammary neoplasms Apc mutation enhances PyMT-induced mammary tumorigenesis Activation of the canonical Wnt/β-catenin pathway in ATF3-induced mammary tumors BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.The transcription factor ATF3 acts as an oncogene in mouse mammary tumorigenesis Genetic mechanisms in Apc-mediated mammary tumorigenesis Phenotypic plasticity in normal breast derived epithelial cells.EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.The BCL9-2 proto-oncogene governs estrogen receptor alpha expression in breast tumorigenesis Key signaling nodes in mammary gland development and cancer: β-catenin.Targeting the embryonic gene Cripto-1 in cancer and beyond.Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.Overexpression of human Cripto-1 in transgenic mice delays mammary gland development and differentiation and induces mammary tumorigenesis Beta-catenin simultaneously induces activation of the p53-p21WAF1 pathway and overexpression of cyclin D1 during squamous differentiation of endometrial carcinoma cells.Dormant Wnt-initiated mammary cancer can participate in reconstituting functional mammary glands.Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors.Effect of glycogen synthase kinase-3 inactivation on mouse mammary gland development and oncogenesis Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis.Transdetermination: Drosophila imaginal disc cells exhibit stem cell-like potency Role of Cripto-1 during epithelial-to-mesenchymal transition in development and cancer.Identity deception: not a crime for a stem cell.Runx2 contributes to the regenerative potential of the mammary epithelium.Cardiac stem cells and mechanisms of myocardial regeneration.A bioluminescence reporter mouse that monitors expression of constitutively active β-catenin IGF1R inhibition in mammary epithelia promotes canonical Wnt signaling and Wnt1-driven tumors Three genes control the timing, the site and the size of blastema formation in Drosophila.Paracrine Wnt signaling both promotes and inhibits human breast tumor growth.Wnt signaling in breast organogenesis.Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells.The role of WNT10B in physiology and disease.Wnt signalling in murine postnatal mammary gland development.Molecular alterations in metaplastic breast carcinoma.Dasatinib inhibits mammary tumour development in a genetically engineered mouse model.

P2860

Q24791466-A70EED31-89F4-448C-B9D7-2B423EECF5F9 Q24794618-676A1FDD-72EA-4197-91D3-E038F3173D77 Q24795343-37D82952-0CD6-4FAA-ABB2-3D6DB839C089 Q24795869-1A4C361B-2572-42C4-993D-173F8517B9B1 Q27310772-3B077C7A-0F0D-4814-96FA-DDA7564E3ED0 Q27437626-43CDF2F8-11D8-4183-A29E-55E1051E0637 Q28510331-D6B6A4FF-275D-4540-869D-190A85E8239D Q28584971-05D9C5D2-DD33-46C5-AB0D-820A70E39018 Q28910487-74469FC9-9FEA-4460-A21F-4E75C8824684 Q30496322-3F379A55-8F27-47E1-A92E-E4FA56DB2575 Q33371124-8C7D7F13-6C11-41C5-9598-1786CEDFF7BD Q33406237-517D4085-C189-40D6-9FB7-B7C8934B3EA8 Q33789073-77BAA181-0F98-407D-AEAD-678D968C96CB Q34288822-2362EDE0-D8F1-4F5A-ADEC-37F1EF4EA899 Q34334394-9D4AC92D-ADA8-44D5-8F75-3C5D13683F0B Q34613461-0BAEF2E6-E485-4237-9B08-25061796531B Q34688767-6ACCDE30-641D-47DF-874F-89550291D3D1 Q34698214-2140222C-9B0A-4607-97E3-9F7B73426755 Q35085039-B65B441B-FFD2-440C-AD71-C5DCAF3CD0D6 Q35098096-B756CC80-3222-4CE3-B107-41803F629654 Q35641656-E65E26D1-9D8D-483A-A20C-19EEB22925F5 Q35789027-1FC93C61-6EFE-4A0F-B4C9-2278FAAA15ED Q35815397-9639D14D-65E3-46BC-97CE-A95DB2986250 Q35964137-307ECDEB-DA15-40EB-8541-B7CB5C11FEE8 Q36025249-084980AF-391D-4DAA-8DC5-B7308DC29F06 Q36044923-B222F10D-7670-4312-B526-77F8005C54B6 Q36124315-5CF9C89A-D8EE-4A45-9CC1-C48CEC9C4876 Q36189136-43ADD9E2-E217-4AC9-AD34-37B03190CE38 Q36267790-3885A4A7-8369-4ABE-84EE-1808EBC73188 Q36295368-2917628A-4CA3-48B0-93D0-7B213CF90D5B Q36664343-52278BD4-72F5-411A-9FE7-E2B2B9A07E2C Q36790002-1A99F291-3568-4FDF-9A50-1E6C61D06CFB Q36798949-31FF69D9-5D95-432F-AF10-39C278EEE876 Q37080183-DCC0B29B-EE4A-4840-875F-974BB58A6354 Q37259094-A7202A06-4D7F-4C19-9ABD-897E29040921 Q37394982-5E8125EA-0878-4D4C-8E3D-CCCE1A47A12E Q37859090-291E3246-ADC2-4C78-A45E-4EF126219C4E Q37868761-6DEA6010-587F-40B0-BE60-BF4E17BFD1BD Q38078338-45BF2149-5588-41D5-8D14-16F4F70A3360 Q39160945-EB86659F-EAAB-41FE-94D3-CF4B574A53D1

P2860

Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.

http://www.wikidata.org/entity/Q33897191

description

2002 nî lūn-bûn

@nan

2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年学术文章

@wuu

2002年学术文章

@zh-cn

2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

name

Activation of beta -catenin si ...... rmis and squamous metaplasias.

@ast

Activation of beta -catenin si ...... rmis and squamous metaplasias.

@en

type

label

Activation of beta -catenin si ...... rmis and squamous metaplasias.

@ast

Activation of beta -catenin si ...... rmis and squamous metaplasias.

@en

prefLabel

Activation of beta -catenin si ...... rmis and squamous metaplasias.

@ast

Activation of beta -catenin si ...... rmis and squamous metaplasias.

@en

P1433

Q33897191-B24E2606-27A4-4718-B316-2BAEDE3ED228

P1476

Q33897191-CB403D3A-9E0C-4196-B318-A322F2D4BFBC

P2093

Q33897191-068ED76A-D9F9-4C61-AEEA-282CE7A5A0E6

Q33897191-44F03230-8915-4DBC-B058-44EB80EF2B8F

Q33897191-62F9482A-958E-481E-85A3-85C6A0084D02

Q33897191-7BE4ECEA-8B7E-4BCD-9709-5993769D5B8E

Q33897191-80303A78-A6A0-4C15-B80A-4B9E7D493E23

Q33897191-B8727077-5DAD-4AD8-983E-56AFA4EC734C

Q33897191-D5F2427C-C29F-421D-99F4-4AEE56E7F483

Q33897191-DE53BFCA-47AB-42E4-A86D-80B2308A7706

Q33897191-F6E203E5-3022-4657-B2E2-59C29F7676ED

P2860

Q33897191-01EB1496-361D-4C08-BB00-C43D20293CCB

Q33897191-17438B6D-2A20-4C32-BF76-09CFA0104552

Q33897191-1E72E51B-7527-46CD-B08A-4BFBD4957660

Q33897191-2154310D-1685-4E9E-89FB-2FAF05C2D767

Q33897191-365DA2F0-D0B2-4592-8325-2E40D5C1A471

Q33897191-4B6B3442-6513-418C-AF0D-A9349FA0A72C

Q33897191-4F8F43A4-27D7-4ECC-887E-91A669CBFF86

Q33897191-7000BBF8-46F9-4097-97AF-DD9C233D04C3

Q33897191-D56D561A-BF2B-484F-B9EC-D50544238E82

Q33897191-DE6FEE09-8D45-4103-B69B-F3E80DCBA386

P304

Q33897191-9A19ACCB-C885-4C55-BB48-734AFD053201

P31

Q33897191-D7677C6F-8278-4269-8C9B-0ECA31459694

P356

Q33897191-A34DE957-6D99-478F-A4B4-FD84959983D6

P407

Q33897191-869298D2-CD9C-44DD-BCC9-DFF7280714EE

P433

Q33897191-48BB1523-D118-4806-9D75-820A4070401D

P478

Q33897191-6150827B-ECEC-4D7D-A08F-EA2F8F35BBA1

P50

Q33897191-C0289E85-FA2D-4680-A578-13B408B52525

P577

Q33897191-F2493885-066A-437C-B11A-68EF1BB606C4

P5875

Q33897191-36CEC1C5-E76D-46E7-9B30-6971B0F21EE8

P698

Q33897191-F96B69E8-A693-41E2-8B64-61939A3FEBBA

P932

Q33897191-1F2743DB-1ECA-4ADB-B2B7-921FFCDC8499

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Activation of beta -catenin si ...... ermis and squamous metaplasias

@en

P2093

Fabienne Le Provost

http://www.w3.org/2001/XMLSchema#string

Fotini Gounari

http://www.w3.org/2001/XMLSchema#string

Harald von Boehmer

http://www.w3.org/2001/XMLSchema#string

Jonathan M Shillingford

http://www.w3.org/2001/XMLSchema#string

Keiko Miyoshi

http://www.w3.org/2001/XMLSchema#string

Khashayarsha Khazaie

http://www.w3.org/2001/XMLSchema#string

Makoto M Taketo

http://www.w3.org/2001/XMLSchema#string

Robert D Cardiff

http://www.w3.org/2001/XMLSchema#string

Roderick Bronson

http://www.w3.org/2001/XMLSchema#string

P2860

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin

Lack of beta-catenin affects mouse development at gastrulation

Requirement for beta-catenin in anterior-posterior axis formation in mice

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer.

Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

Cre-mediated gene deletion in the mammary gland.

Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland.

P304

219-224

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.012414099

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

99

http://www.w3.org/2001/XMLSchema#string

P50

Lothar Hennighausen

P577

2002-01-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11583627

http://www.w3.org/2001/XMLSchema#string

P698

11773619

http://www.w3.org/2001/XMLSchema#string

P932

117542

http://www.w3.org/2001/XMLSchema#string