Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase. - Test2 - elhamkhani - TriplyDB

Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase.

Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase.

http://www.wikidata.org/entity/Q33904366

about

Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development Kinases as druggable targets in trypanosomatid protozoan parasites Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion.Disruption of TgPHIL1 alters specific parameters of Toxoplasma gondii motility measured in a quantitative, three-dimensional live motility assay Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress The Cryptosporidium parvum Kinome Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase A schistosome cAMP-dependent protein kinase catalytic subunit is essential for parasite viability Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase Distinct signalling pathways control Toxoplasma egress and host-cell invasion Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii Serum Albumin Stimulates Protein Kinase G-dependent Microneme Secretion in Toxoplasma gondii The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony.Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni.Quantitative in vivo analyses reveal calcium-dependent phosphorylation sites and identifies a novel component of the Toxoplasma invasion motor complex The systematic functional analysis of Plasmodium protein kinases identifies essential regulators of mosquito transmission Toxoplasma gondii: the model apicomplexan.Mechanisms of Toxoplasma gondii persistence and latency.Toxoplasma gondii: determinants of tachyzoite to bradyzoite conversion.Drug Repurposing Screening Identifies Novel Compounds That Effectively Inhibit Toxoplasma gondii Growth The role of cGMP signalling in regulating life cycle progression of Plasmodium.Screening and synthesis: high throughput technologies applied to parasitology.Antimalarial drug discovery: targeting protein kinases.The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements.Calcium-dependent signaling and kinases in apicomplexan parasites.Review of Experimental Compounds Demonstrating Anti-Toxoplasma Activity.Cyclic nucleotide signalling in malaria parasites.Cyclic-nucleotide signalling in protozoa.Plasmodium kinases as targets for new-generation antimalarials.Protein kinases of Toxoplasma gondii: functions and drug targets.Toxoplasma development - turn the switch on or off?Antiplasmodial drug targets: a patent review (2000 - 2013).Enzyme Activity Assays for Protein Kinases: Strategies to Identify Active Substrates.Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites.Invasion of hepatocytes by Plasmodium sporozoites requires cGMP-dependent protein kinase and calcium dependent protein kinase 4.Nitric oxide maintains cell survival of Trichomonas vaginalis upon iron depletion.AID-ing Signaling in Toxoplasma gondii

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Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase.

http://www.wikidata.org/entity/Q33904366

description

2002 nî lūn-bûn

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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2002 թվականի հունիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Toxoplasma gondii cyclic GMP-d ...... ntial parasite protein kinase.

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Toxoplasma gondii cyclic GMP-d ...... ntial parasite protein kinase.

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Toxoplasma gondii cyclic GMP-d ...... ntial parasite protein kinase.

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EC.1.3.317-328.2002

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Eukaryotic Cell

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Toxoplasma gondii cyclic GMP-d ...... ntial parasite protein kinase.

@en

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Bakela Nare

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John Allocco

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Judyann Wiltsie

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Paul A Liberator

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Robert G K Donald

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Scott P Salowe

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Suresh B Singh

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P2860

Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

Structural basis of inhibitor selectivity in MAP kinases

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

Accurate modeling of protein conformation by automatic segment matching

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome.

Assessment of therapy for toxoplasma encephalitis. The TE Study Group.

Cyclic GMP-dependent protein kinases: understanding in vivo functions by gene targeting.

Cyclic nucleotide-dependent protein kinases: intracellular receptors for cAMP and cGMP action.

ATP site-directed competitive and irreversible inhibitors of protein kinases.

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317-328

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Toxoplasma gondii

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118020

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