Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats
about
Endocrine fibroblast growth factors 15/19 and 21: from feast to famineIntegrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivoNon-sympathetic control of brown adipose tissueFibroblast Growth Factor Signaling in Metabolic RegulationFGF21, energy expenditure and weight loss - How much brown fat do you need?Inventing new medicines: The FGF21 storyThe brain and brown fatNeural control of energy balance: translating circuits to therapiesFGF21 as a Stress Hormone: The Roles of FGF21 in Stress Adaptation and the Treatment of Metabolic DiseasesRegulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted stateProtein-dependent regulation of feeding and metabolismRationale-Based Engineering of a Potent Long-Acting FGF21 Analog for the Treatment of Type 2 DiabetesFGF-21, a novel metabolic regulator, has a robust neuroprotective role and is markedly elevated in neurons by mood stabilizersFGF21 is an endocrine signal of protein restrictionGenome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intakeCCL5/RANTES contributes to hypothalamic insulin signaling for systemic insulin responsiveness through CCR5.Metabolic role of fibroblast growth factor 21 in liver, adipose and nervous system tissues.Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss.Novel locus including FGF21 is associated with dietary macronutrient intake.Cellular mechanisms by which FGF21 improves insulin sensitivity in male miceFibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult miceGenetic determinants of atherosclerosis, obesity, and energy balance in consomic mice.Lower cerebrospinal fluid/plasma fibroblast growth factor 21 (FGF21) ratios and placental FGF21 production in gestational diabetesTissue-specific actions of the metabolic hormones FGF15/19 and FGF21.Thermogenic activation induces FGF21 expression and release in brown adipose tissue.Liraglutide, leptin and their combined effects on feeding: additive intake reduction through common intracellular signalling mechanisms.Receptor antibodies as novel therapeutics for diabetes.Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes.Fibroblast growth factor 21 (FGF21) in human cerebrospinal fluid: relationship with plasma FGF21 and body adiposity.Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet-induced obese and leptin-deficient obese miceCentral angiotensin II has catabolic action at white and brown adipose tissueCentral Fibroblast Growth Factor 21 Browns White Fat via Sympathetic Action in Male Mice.Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice.FGF21 deletion exacerbates diabetic cardiomyopathy by aggravating cardiac lipid accumulation.Glucose intolerance induced by blockade of central FGF receptors is linked to an acute stress responseDietary restriction in obese children and its relation with eating behavior, fibroblast growth factor 21 and leptin: a prospective clinical intervention study.The impact of polyphenols on chondrocyte growth and survival: a preliminary reportβKlotho is required for fibroblast growth factor 21 effects on growth and metabolismErythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice.
P2860
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P2860
Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats
description
2010 nî lūn-bûn
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2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@ast
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@en
type
label
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@ast
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@en
prefLabel
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@ast
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@en
P2093
P2860
P356
P1433
P1476
Fibroblast growth factor 21 ac ...... ulin sensitivity in obese rats
@en
P2093
David A Sarruf
Gregory J Morton
Jonathan D Fischer
Jonathan German
Joshua P Thaler
Kayoko Ogimoto
Michael W Schwartz
P2860
P304
P356
10.2337/DB09-1878
P407
P577
2010-03-31T00:00:00Z