about
Abnormalities of B cell phenotype, immunoglobulin gene expression and the emergence of autoimmunity in Sjögren's syndromeBasal immunoglobulin signaling actively maintains developmental stage in immature B cells.Resolve, revise, and relax: the 3 Rs of B cell repertoire adjustmentOrchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signallingHuman antibody production in transgenic animalsSecondary receptor editing in the generation of autoimmunityFocused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep SequencingYY1 controls Igκ repertoire and B-cell development, and localizes with condensin on the Igκ locusImmunoglobulin heavy chain variable region gene replacement As a mechanism for receptor revision in rheumatoid arthritis synovial tissue B lymphocytesAnalysis of RAG expression by peripheral blood CD5+ and CD5- B cells of patients with childhood systemic lupus erythematosusPatterns of receptor revision in the immunoglobulin heavy chains of a teleost fishPhenotypic characterization of autoreactive B cells--checkpoints of B cell tolerance in patients with systemic lupus erythematosusConserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells.Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen.Mechanisms promoting translocations in editing and switching peripheral B cells.Specific in vivo deletion of B-cell subpopulations expressing human immunoglobulins by the B-cell superantigen protein L.B-cell-lineage immunogen design in vaccine development with HIV-1 as a case studyProduction of IgG autoantibody requires expression of activation-induced deaminase in early-developing B cells in a mouse model of SLE.Soma-to-germline feedback is implied by the extreme polymorphism at IGHV relative to MHC: The manifest polymorphism of the MHC appears greatly exceeded at Immunoglobulin loci, suggesting antigen-selected somatic V mutants penetrate Weismann's BarrieResponsiveness of B cells is regulated by the hinge region of IgD.Immunoglobulin variable-region gene usage in systemic autoimmune diseases.Receptor editing in lymphocyte development and central tolerance.Subversion of B lymphocyte tolerance by hydralazine, a potential mechanism for drug-induced lupus.Contribution of V(H) replacement products in mouse antibody repertoire.Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients.Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion.Systematic confirmation study of GWAS-identified genetic variants for Kawasaki disease in a Chinese population.Systematic analysis of sequences of anti-DNA antibodies--relevance to theories of origin and pathogenicity.Diverse immunoglobulin light chain organizations in fish retain potential to revise B cell receptor specificitiesVH Replacement Footprint Analyzer-I, a Java-Based Computer Program for Analyses of Immunoglobulin Heavy Chain Genes and Potential VH Replacement Products in Human and MouseHeavy-chain receptor editing unbound.The role of DNA breaks in genomic instability and tumorigenesis.Accumulation of VH Replacement Products in IgH Genes Derived from Autoimmune Diseases and Anti-Viral Responses in Human.The transcription factor Bright plays a role in marginal zone B lymphocyte development and autoantibody production.Forced usage of positively charged amino acids in immunoglobulin CDR-H3 impairs B cell development and antibody production.Gene-targeted mice lacking the Trex1 (DNase III) 3'-->5' DNA exonuclease develop inflammatory myocarditis.The molecular basis and biological significance of VH replacement.Similarities and differences between the light and heavy chain Ig variable region gene repertoires in chronic lymphocytic leukemia.Efficient generation of B lymphocytes by recognition of self-antigens.
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Revising B cell receptors
@ast
Revising B cell receptors
@en
type
label
Revising B cell receptors
@ast
Revising B cell receptors
@en
prefLabel
Revising B cell receptors
@ast
Revising B cell receptors
@en
P2860
P921
P356
P1476
Revising B cell receptors
@en
P2093
P2860
P304
P356
10.1084/JEM.191.11.1813
P407
P577
2000-06-01T00:00:00Z
2000-06-05T00:00:00Z