RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing. - Test2 - elhamkhani - TriplyDB

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

http://www.wikidata.org/entity/Q33944218

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Matrin3: connecting gene expression with the nuclear matrix Clinical and Mechanistic Insights Into the Genetics of Cardiomyopathy hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function Modeling structural and functional deficiencies of RBM20 familial dilated cardiomyopathy using human induced pluripotent stem cells Titin-truncating variants affect heart function in disease cohorts and the general population.Alternative Splicing Signatures in RNA-seq Data: Percent Spliced in (PSI).Delineating RBM20 regulation of alternative splicing in dilated cardiomyopathy Computational challenges, tools, and resources for analyzing co- and post-transcriptional events in high throughput.RBFox1-mediated RNA splicing regulates cardiac hypertrophy and heart failure Cross-talk between PRMT1-mediated methylation and ubiquitylation on RBM15 controls RNA splicing.Pharmacological Modulation of Calcium Homeostasis in Familial Dilated Cardiomyopathy: An In Vitro Analysis From an RBM20 Patient-Derived iPSC Model Molecular Characterization of Pediatric Restrictive Cardiomyopathy from Integrative Genomics LOX-1 and Its Splice Variants: A New Challenge for Atherosclerosis and Cancer-Targeted Therapies.Functional roles of alternative splicing factors in human disease.Cardiac cytoarchitecture - why the "hardware" is important for heart function!Abnormalities in Alternative Splicing of Apoptotic Genes and Cardiovascular Diseases.RBM20, a potential target for treatment of cardiomyopathy via titin isoform switching.Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems.Emerging roles for RNA-binding proteins as effectors and regulators of cardiovascular disease.Pre-mRNA mis-splicing of sarcomeric genes in heart failure.Genetics and Genomics of Single-Gene Cardiovascular Diseases: Common Hereditary Cardiomyopathies as Prototypes of Single-Gene Disorders.CircRNAs: a regulator of cellular stress.Alternative splicing as a regulator of development and tissue identity.Overview of the Muscle Cytoskeleton.Genetics of paediatric cardiomyopathies.The emerging role of alternative splicing in senescence and aging.Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy.Reducing RBM20 activity improves diastolic dysfunction and cardiac atrophy.Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction.Alternative Splicing of NOX4 in the Failing Human Heart.Muscle-Specific Mis-Splicing and Heart Disease Exemplified by RBM20.Editor's Highlight: The Altered DNA Methylome of Chronic Doxorubicin Exposure in Sprague Dawley Rats.cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation.Putative functional genes in idiopathic dilated cardiomyopathy.Diagnostic Yield of Whole Exome Sequencing in Pediatric Dilated Cardiomyopathy.Dilated Cardiomyopathy: Genetic Determinants and Mechanisms.A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism.RBM20 and RBM24 cooperatively promote the expression of short enh splice variants.Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons.Molecular basis of titin exon exclusion by RBM20 and the novel titin splice regulator PTB4.

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P2860

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

http://www.wikidata.org/entity/Q33944218

description

2014 nî lūn-bûn

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2014 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հունիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@ast

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@en

type

label

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@ast

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@en

prefLabel

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@ast

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@en

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P1433

Journal of Clinical Investigation

P1476

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing.

@en

P2093

Carola Rintisch

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Henrike Maatz

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Marieluise Kirchner

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Matthias Selbach

http://www.w3.org/2001/XMLSchema#string

Norbert Hubner

http://www.w3.org/2001/XMLSchema#string

Stuart A Cook

http://www.w3.org/2001/XMLSchema#string

Vita Dauksaite

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2)

RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing

Sorting out the complexity of SR protein functions

The Ensembl genome database project

Using positional distribution to identify splicing elements and predict pre-mRNA processing defects in human genes

Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

TopHat: discovering splice junctions with RNA-Seq

Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs

Alternative isoform regulation in human tissue transcriptomes

P304

3419-3430

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scholarly article

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10.1172/JCI74523

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P407

P433

8

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P478

124

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P50

Nikolaus Rajewsky

Markus Landthaler

Michael Gotthardt

Matthias Heinig

Michael H Radke

Sebastian Schäfer

P577

2014-06-24T00:00:00Z

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24960161

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P932

4109538

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