A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.
about
Identification and functional characterization of an Src homology domain 3 domain-binding site on CblA comprehensive manually curated reaction map of RANKL/RANK-signaling pathwayOsteoimmunology: interactions of the bone and immune systemCbl-b positively regulates Btk-mediated activation of phospholipase C-gamma2 in B cellsKinase AKT controls innate immune cell development and functionS1PR2 links germinal center confinement and growth regulationIdelalisib for the treatment of chronic lymphocytic leukemiaDisabling of receptor activator of nuclear factor-kappaB (RANK) receptor complex by novel osteoprotegerin-like peptidomimetics restores bone loss in vivoThe Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.R-Ras is required for murine dendritic cell maturation and CD4+ T-cell primingCostimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIP(short) via phosphatidylinositol 3-kinase and AKT/protein kinase B.A phase II trial of the Src-kinase inhibitor saracatinib after four cycles of chemotherapy for patients with extensive stage small cell lung cancer: NCCTG trial N-0621.Promising bone-related therapeutic targets for rheumatoid arthritis.Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer.The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond.Src kinase and Syk activation initiate PI3K signaling by a chimeric latent membrane protein 1 in Epstein-Barr virus (EBV)+ B cell lymphomas.CD200R/CD200 inhibits osteoclastogenesis: new mechanism of osteoclast control by mesenchymal stem cells in humanModulation and function of caspase pathways in B lymphocytes.The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions.Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-bc-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses.Cbl-b Deficiency in Mice Results in Exacerbation of Acute and Chronic Stages of Allergic Asthma.p110δ PI3 kinase pathway: emerging roles in cancer.Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia.Molecular mechanism and function of CD40/CD40L engagement in the immune system.Denosumab for treatment of breast cancer bone metastases and beyond.Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family MoleculesTranscriptional program of mouse osteoclast differentiation governed by the macrophage colony-stimulating factor and the ligand for the receptor activator of NFkappa B.Signaling mechanisms regulating B-lymphocyte activation and tolerance.Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation.Modulation of Immune Cell Functions by the E3 Ligase Cbl-b.Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system.LMP1 signaling pathway activates IRF4 in latent EBV infection and a positive circuit between PI3K and Src is required.Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion.OX40 complexes with phosphoinositide 3-kinase and protein kinase B (PKB) to augment TCR-dependent PKB signalingEpstein-Barr virus-encoded latent membrane protein 1 activates beta-catenin signaling in B lymphocytes.CD40/CD40 homodimers are required for CD40-induced phosphatidylinositol 3-kinase-dependent expression of B7.2 by human B lymphocytes.
P2860
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P2860
A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A positive regulatory role for ...... CD40L-mediated Akt activation.
@ast
A positive regulatory role for ...... CD40L-mediated Akt activation.
@en
type
label
A positive regulatory role for ...... CD40L-mediated Akt activation.
@ast
A positive regulatory role for ...... CD40L-mediated Akt activation.
@en
prefLabel
A positive regulatory role for ...... CD40L-mediated Akt activation.
@ast
A positive regulatory role for ...... CD40L-mediated Akt activation.
@en
P2093
P2860
P356
P1476
A positive regulatory role for ...... CD40L-mediated Akt activation
@en
P2093
P2860
P304
30011-30017
P356
10.1074/JBC.M100414200
P407
P577
2001-06-13T00:00:00Z