Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres.
about
Rap1 prevents telomere fusions by nonhomologous end joining.Def1p is involved in telomere maintenance in budding yeast.Inhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13pIn vitro and ex vivo inhibition of human telomerase by anti-HIV nucleoside reverse transcriptase inhibitors (NRTIs) but not by non-NRTIsYeast telomerase is specialized for C/A-rich RNA templates.Telomeres and telomerase.Human telomerase RNA template sequence is a determinant of telomere repeat extension rate.Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres.Molecular basis for telomere repeat divergence in budding yeastTelomere formation by rap1p binding site arrays reveals end-specific length regulation requirements and active telomeric recombination.Telomeric protein distributions and remodeling through the cell cycle in Saccharomyces cerevisiae.Telomere length, telomere-binding proteins, and DNA damage signaling.Telomere fusions caused by mutating the terminal region of telomeric DNAYeast Est2p affects telomere length by influencing association of Rap1p with telomeric chromatin.Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres.Counting of Rif1p and Rif2p on Saccharomyces cerevisiae telomeres regulates telomere length.The Rap1p-telomere complex does not determine the replicative capacity of telomerase-deficient yeast.Mutant telomere sequences lead to impaired chromosome separation and a unique checkpoint response.Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability.Protein binding to expanded telomere repeats in Tetrahymena thermophila.Processive utilization of the human telomerase template: lack of a requirement for template switching.Chromosome termini of the monocot plant Othocallis siberica are maintained by telomerase, which specifically synthesises vertebrate-type telomere sequences.
P2860
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P2860
Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
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2000年論文
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name
Telomerase RNA template mutati ...... elomerase action at telomeres.
@ast
Telomerase RNA template mutati ...... elomerase action at telomeres.
@en
type
label
Telomerase RNA template mutati ...... elomerase action at telomeres.
@ast
Telomerase RNA template mutati ...... elomerase action at telomeres.
@en
prefLabel
Telomerase RNA template mutati ...... elomerase action at telomeres.
@ast
Telomerase RNA template mutati ...... elomerase action at telomeres.
@en
P2860
P1476
Telomerase RNA template mutati ...... elomerase action at telomeres.
@en
P2093
J C Prescott
P2860
P304
P356
10.1128/MCB.20.8.2941-2948.2000
P407
P577
2000-04-01T00:00:00Z