TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.
about
Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonismEndorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cellsMatrix metalloproteinases in tumorigenesis: an evolving paradigm.Endogenous angiogenesis inhibitor blocks tumor growth via direct and indirect effects on tumor microenvironment.TIMP-2 targets tumor-associated myeloid suppressor cells with effects in cancer immune dysfunction and angiogenesisLow levels of tissue inhibitor of metalloproteinase-2 at birth may be associated with subsequent development of bronchopulmonary dysplasia in preterm infantsAntagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathway.Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear factReduced tissue inhibitor of metalloproteinase-2 expression is associated with advanced medullary thyroid carcinoma.Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic.Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses.The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression.Counterbalance: modulation of VEGF/VEGFR activities by TNFSF15
P2860
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P2860
TIMP-2 modulates VEGFR-2 phosphorylation and enhances phosphodiesterase activity in endothelial cells.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@ast
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@en
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@nl
type
label
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@ast
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@en
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@nl
prefLabel
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@ast
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@en
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells.
@nl
P2093
P2860
P1476
TIMP-2 modulates VEGFR-2 phosp ...... activity in endothelial cells
@en
P2093
Bei-yang Wei
Patricia S Tsang
Seo-Jin Lee
Tere M Diaz
P2860
P2888
P304
P356
10.1038/LABINVEST.2009.136
P577
2010-01-18T00:00:00Z
P5875
P6179
1048208990