Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice - Test2 - elhamkhani - TriplyDB

Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice

Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice

http://www.wikidata.org/entity/Q34023627

about

Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia Abnormal striatal dopaminergic neurotransmission during rest and task production in spasmodic dysphonia.TorsinA hypofunction causes abnormal twisting movements and sensorimotor circuit neurodegeneration A novel conditional knock-in approach defines molecular and circuit effects of the DYT1 dystonia mutation.Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA.Abnormal nuclear envelope in the cerebellar Purkinje cells and impaired motor learning in DYT11 myoclonus-dystonia mouse models Untethering the nuclear envelope and cytoskeleton: biologically distinct dystonias arising from a common cellular dysfunction Decreased dopamine receptor 1 activity and impaired motor-skill transfer in Dyt1 ΔGAG heterozygous knock-in mice.Pre-synaptic release deficits in a DYT1 dystonia mouse model.Behavioral and electrophysiological characterization of Dyt1 heterozygous knockout mice.Abnormal nuclear envelopes in the striatum and motor deficits in DYT11 myoclonus-dystonia mouse models Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons.Improved motor performance in Dyt1 ΔGAG heterozygous knock-in mice by cerebellar Purkinje-cell specific Dyt1 conditional knocking-out Mouse models of neurodevelopmental disease of the basal ganglia and associated circuits.Functional analysis of dopaminergic systems in a DYT1 knock-in mouse model of dystonia.Engineering animal models of dystonia A role for cerebellum in the hereditary dystonia DYT1.Current Opinions and Areas of Consensus on the Role of the Cerebellum in Dystonia.Electromyographic evidence in support of a knock-in mouse model of DYT1 Dystonia.Neurogenesis and neuronal migration in the forebrain of the TorsinA knockout mouse embryo.Miniature release events of glutamate from hippocampal neurons are influenced by the dystonia-associated protein torsinA.How Many Types of Dystonia? Pathophysiological Considerations.

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Motor deficits and decreased striatal dopamine receptor 2 binding activity in the striatum-specific Dyt1 conditional knockout mice

http://www.wikidata.org/entity/Q34023627

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2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Motor deficits and decreased s ...... Dyt1 conditional knockout mice

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Fumiaki Yokoi

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Jianyong Li

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Mai Tu Dang

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Yuqing Li

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P2860

The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro

Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

Dopamine D2 long receptor-deficient mice display alterations in striatum-dependent functions

Loss of the dystonia-associated protein torsinA selectively disrupts the neuronal nuclear envelope

Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum

A molecular mechanism underlying the neural-specific defect in torsinA mutant mice

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells

Increased c-fos expression in the central nucleus of the amygdala and enhancement of cued fear memory in Dyt1 DeltaGAG knock-in mice

Dichotomous dopaminergic control of striatal synaptic plasticity.

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10.1371/JOURNAL.PONE.0024539

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9

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David G. Standaert

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2011-09-12T00:00:00Z

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51655769

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corpus striatum

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3171455

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