Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli
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Gene duplication as a mechanism of genomic adaptation to a changing environmentParallel Mapping of Antibiotic Resistance Alleles in Escherichia coliRapid bursts and slow declines: on the possible evolutionary trajectories of enzymesPhysiological Function of Rac Prophage During Biofilm Formation and Regulation of Rac Excision in Escherichia coli K-12Electrostatic mis-interactions cause overexpression toxicity of proteins in E. coliMechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.Tackling Drug Resistant Infection Outbreaks of Global Pandemic Escherichia coli ST131 Using Evolutionary and Epidemiological Genomics.The role of cellular objectives and selective pressures in metabolic pathway evolution.A retrosynthetic biology approach to metabolic pathway design for therapeutic productionNetwork-level architecture and the evolutionary potential of underground metabolism.Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial geneticsEscherichia coli D-malate dehydrogenase, a generalist enzyme active in the leucine biosynthesis pathwayHigh incidence of multiple antibiotic resistant cells in cultures of in enterohemorrhagic Escherichia coli O157:H7.A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress.Evolving promiscuously.Identifying feasible metabolic routes in Mycobacterium smegmatis and possible alterations under diverse nutrient conditions.Toward a systems biology perspective on enzyme evolution.Escherichia coli ASKA Clone Library Harboring tRNA-Specific Adenosine Deaminase (tadA) Reveals Resistance towards Xanthorrhizol.Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates.Fumarate-Mediated Persistence of Escherichia coli against Antibiotics.Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5'-Phosphate Production in E. coliGenomewide overexpression screen for fosfomycin resistance in Escherichia coli: MurA confers clinical resistance at low fitness costInsight into determinants of substrate binding and transport in a multidrug efflux protein.The in vitro and in vivo effects of constitutive light expression on a bioluminescent strain of the mouse enteropathogen Citrobacter rodentium.Tracking Cefoperazone/Sulbactam Resistance Development In vivo in A. baumannii Isolated from a Patient with Hospital-Acquired Pneumonia by Whole-Genome SequencingSubstrate ambiguous enzymes within the Escherichia coli proteome offer different evolutionary solutions to the same problem.Combinatorial approaches for inverse metabolic engineering applications.Enzyme recruitment and its role in metabolic expansion.The intrinsic resistome of bacterial pathogens.Copy number change: evolving views on gene amplification.Adaptations of anaerobic archaea to life under extreme energy limitation.Dynamics and constraints of enzyme evolution.Yeast: a microbe with macro-implications to antimicrobial drug discovery.Complex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.YeeO from Escherichia coli exports flavinsLon protease inactivation, or translocation of the lon gene, potentiate bacterial evolution to antibiotic resistance.Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity.Parallel Evolution of High-Level Aminoglycoside Resistance in Escherichia coli Under Low and High Mutation Supply Rates.Increased gene dosage plays a predominant role in the initial stages of evolution of duplicate TEM-1 beta lactamase genes.Editorial comment to genome-wide transcriptome analysis of fluoroquinolone resistance in clinical isolates of Escherichia coli.
P2860
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P2860
Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coli
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Artificial gene amplification ...... terminants in Escherichia coli
@ast
Artificial gene amplification ...... terminants in Escherichia coli
@en
Artificial gene amplification ...... terminants in Escherichia coli
@nl
type
label
Artificial gene amplification ...... terminants in Escherichia coli
@ast
Artificial gene amplification ...... terminants in Escherichia coli
@en
Artificial gene amplification ...... terminants in Escherichia coli
@nl
prefLabel
Artificial gene amplification ...... terminants in Escherichia coli
@ast
Artificial gene amplification ...... terminants in Escherichia coli
@en
Artificial gene amplification ...... terminants in Escherichia coli
@nl
P2860
P356
P1476
Artificial gene amplification ...... terminants in Escherichia coli
@en
P2093
Paulina Hanson-Manful
Valerie W C Soo
P2860
P304
P356
10.1073/PNAS.1012108108
P407
P577
2010-12-20T00:00:00Z