Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines - Test2 - elhamkhani - TriplyDB

Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

http://www.wikidata.org/entity/Q34039588

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International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors Opposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation.Altered esophageal histamine receptor expression in Eosinophilic Esophagitis (EoE): implications on disease pathogenesis.Thioperamide induces CD4 CD25 Foxp3 regulatory T lymphocytes in the lung mucosa of allergic mice through its action on dendritic cells.Expression and function of histamine and its receptors in atopic dermatitis Sequential engagement of FcεRI on Mast Cells and Basophil Histamine H(4) Receptor and FcεRI in Allergic Rhinitis.Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo.Antagonism of histamine H4 receptors exacerbates clinical and pathological signs of experimental autoimmune encephalomyelitis.Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide.Mast cells in allergic asthma and beyond.Antihistamines in ocular allergy: are they all created equal?Histamine H4 receptor ligands and their potential therapeutic applications: an update.The histamine H4 receptor: from orphan to the clinic.Clinical Development of Histamine H4 Receptor Antagonists.Effect of H4R antagonist N-(2-aminoethyl)-5-chloro-1H-indol-2-carboxamides and 5-chloro-2-(piperazin-1-ylmethyl)-1H-benzimidazole on histamine and 4-methylhistamine-induced mast cell response.The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis Lack of Histamine H4-Receptor Expression Aggravates TNBS-Induced Acute Colitis Symptoms in Mice.Synthesis and functional characterization of imbutamine analogs as histamine H3 and H4 receptor ligands.Synthesis and histamine H(3) and H(4) receptor activity of conformationally restricted cyanoguanidines related to UR-PI376.Combined blockade of the histamine H1 and H4 receptor suppresses peanut-induced intestinal anaphylaxis by regulating dendritic cell function.Histamine-induced changes in rat tracheal goblet cell mucin store and mucosal edema.The dual H3/4R antagonist thioperamide does not fully mimic the effects of the 'standard' H4R antagonist JNJ 7777120 in experimental murine asthma.Ouabain attenuates ovalbumin-induced airway inflammation.Role of the Histamine H4-Receptor in Bronchial Asthma.Histamine H4 receptor knockout mice display reduced inflammation in a chronic model of atopic dermatitis.Histamine regulates autoreactive T cell activation and adhesiveness in inflamed brain microcirculation.Mapping histamine H4receptor–ligand binding modes The Role of Histamine H4 Receptor in Asthma and Atopic Dermatitis Histamine H4 receptor activation enhances LPS-induced IL-6 production in mast cells via ERK and PI3K activation P-FN12, an H4R-Based Epitope Vaccine Screened by Phage Display, Regulates the Th1/Th2 Balance in Rat Allergic Rhinitis

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P2860

Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

http://www.wikidata.org/entity/Q34039588

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Respiratory Research

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Histamine H4 receptor antagoni ...... ia modulation of Th2 cytokines

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Jason P Riley

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Jeffery M Cowden

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Jing Ying Ma

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Paul J Dunford

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P2860

Interleukin-13: central mediator of allergic asthma

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties

Asthma. From bronchoconstriction to airways inflammation and remodeling.

Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Tokyo Joshi-Idai Asthma Research Group.

Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness

Measuring lung function in mice: the phenotyping uncertainty principle.

Neutrophil histamine contributes to inflammation in mycoplasma pneumonia.

Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice.

Recent progress in the biology of airway dendritic cells and implications for understanding the regulation of asthmatic inflammation.

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Robin L. Thurmond

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