A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
about
International Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsModulation of neutrophil oxidative burst via histamine receptorsH4 histamine receptors mediate cell cycle arrest in growth factor-induced murine and human hematopoietic progenitor cellsDOGS: reaction-driven de novo design of bioactive compoundsOrganic cation transporter 3 modulates murine basophil functions by controlling intracellular histamine levelsLuciferase reporter gene assay on human, murine and rat histamine H4 receptor orthologs: correlations and discrepancies between distal and proximal readoutsSequential application of ligand and structure based modeling approaches to index chemicals for their hH4R antagonismThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsStructural basis for inhibition of histamine N-methyltransferase by diverse drugsHistamine: new thoughts about a familiar mediator.Histamine H4 receptor as a new therapeutic target for choroidal neovascularization in age-related macular degenerationHistamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokinesOpposite effects of mepyramine on JNJ 7777120-induced amelioration of experimentally induced asthma in mice in sensitization and provocation.Ebastine in the light of CONGA recommendations for the development of third-generation antihistaminesThe role of histamine H4 receptor in immune and inflammatory disordersDistinct signalling pathways of murine histamine H1- and H4-receptors expressed at comparable levels in HEK293 cells.Suppression of Laser-Induced Choroidal Neovascularization by the Oral Medicine Targeting Histamine Receptor H4 in Mice.Histamine in allergic inflammation and immune modulation.Roles of histamine and its receptors in allergic and inflammatory bowel diseases.Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability.The histamine H4 receptor in autoimmune disease.Antagonism of the histamine H4 receptor reduces LPS-induced TNF production in vivo.Anti-Inflammatory mechanisms of enteric Heligmosomoides polygyrus infection against trinitrobenzene sulfonic acid-induced colitis in a murine model.In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties.Molecular and cellular analysis of human histamine receptor subtypes.Molecular and biochemical pharmacology of the histamine H4 receptor.Histamine H4 receptor ligands and their potential therapeutic applications.Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide.Histamine H3 and H4 receptors as novel drug targets.Immunomodulation using agonists and antagonists: potential clinical applications.Histamine H4 receptor ligands and their potential therapeutic applications: an update.Investigational drugs for pruritus.Histamine H4 receptor ligands: future applications and state of art.Histamine H₄ receptors in the gastrointestinal tract.The histamine H4 receptor: from orphan to the clinic.Activation of the ileal neuroendocrine tumor cell line P-STS by acetylcholine is amplified by histamine: role of H3R and H4R.Looking forward to new targeted treatments for chronic spontaneous urticaria.Clinical Development of Histamine H4 Receptor Antagonists.Pharmacological Characterization of Human Histamine Receptors and Histamine Receptor Mutants in the Sf9 Cell Expression System.The histamine H4 receptor is a potent inhibitor of adhesion-dependent degranulation in human neutrophils.
P2860
Q26827568-9DDD28FF-CB17-46D8-B1EC-062C51C7C95EQ26998785-6F5E8EF2-76DF-4FDE-8068-CCA3AD677DA6Q28475930-5CD812C5-B8C7-4A20-84D6-80F3736F9A4DQ28480868-B8E4880B-0B83-4357-8673-82A40251469CQ28510476-BCBF6B16-17CA-400A-B6EA-7E19907A13F5Q28536518-C66E9BEA-CA47-437A-8893-1D61E3B708C5Q28543874-43B3C4A8-E330-47D7-8B21-AECFA203C659Q30486707-B752C4FB-ECF7-446E-8880-C2344F999296Q33613450-64BE3FA6-892D-4305-A4FD-1FBEA21E1D04Q33778157-64D0785E-E3E8-4A56-9200-B757C539A383Q34025192-6C3E61B4-FC14-4608-834D-ECD446E2736FQ34039588-F011FE6F-CB70-423C-8722-C44C254992ACQ34137632-DBE5FF97-ED99-411C-89E9-12CA15D620C7Q34623813-E5DC394A-94B4-4D4D-929D-D228D75FAEE7Q34967790-CD553BFC-A9C7-4F8B-9EEC-FEC2F714FD6FQ35268844-94C4D655-5D7B-4CEF-931F-8221B1531A14Q35577903-CECE3342-6B3A-4F61-8D69-4D64A575DA54Q36098788-FAF01C2D-8E4A-4D33-8CEE-CB652DB2D14BQ36132180-9B5DDC3A-AFB2-4D9E-86E8-478E0BFE769FQ36619798-7885FA7A-32DD-4DBB-AE48-7913BFF65A3DQ36623087-FC5880C7-9317-4976-9FD7-4A07F6E19109Q36844550-92683914-7AC4-4F66-A5B3-3D3C435AB4E2Q36898582-683167AE-6805-4217-9A31-95740316CBCBQ37230881-8A0A75B8-3582-4048-AA25-B3E7E2415892Q37407709-DD8786AD-B43D-40B3-9CD8-BD5F76D206D3Q37469102-A882ADC9-FE34-4CB7-A225-3A06614E16B7Q37481276-49C867C5-6062-4E93-BBB8-AF112056F0E9Q37553620-2AFBFFDB-243E-4D4E-93B4-D97691A6A767Q37598261-EF7C1AF1-74AC-4CFA-AF2C-B02B1BCBA289Q37965728-02DFB157-1F4D-40F1-9EA1-2493FAA61A48Q37990004-AB66EAE4-2BC6-46DE-BF4F-9038495D24C6Q38118383-9A3E62D6-CC77-4915-B79B-0337ECBD2BFAQ38250258-8F9515C6-860D-4D5B-AA66-96108ED74246Q38264340-860479E1-594C-4312-B3AC-8DAB6485304EQ38421144-9C0203C4-7102-44AE-9C4B-4E0F44ADE582Q38705128-C5DB2462-0B15-4E44-9A2B-D1C3296ED17CQ38771632-F0F467A1-23B2-4C80-A318-B1A1C70080FDQ38944794-72AC7ABD-F374-4A27-ADDB-6A5288612858Q38944804-F74E8EE4-A811-4ECE-A354-136C1A114608Q38998092-DA405B70-7947-4481-8910-97913D72BB51
P2860
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im April 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/04/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/01)
@nl
наукова стаття, опублікована у квітні 2004
@uk
مقالة علمية (نشرت في أبريل 2004)
@ar
name
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@ast
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@en
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@nl
type
label
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@ast
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@en
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@nl
prefLabel
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@ast
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@en
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@nl
P2093
P356
P1476
A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties
@en
P2093
Claudia L. Hofstra
James P. Edwards
Jason P. Riley
Kacy N. Williams
Paul J. Dunford
Pragnya J. Desai
Siquan Sun
Steven Nguyen
Wai-Ping Fung-Leung
P304
P356
10.1124/JPET.103.061754
P407
P577
2004-04-01T00:00:00Z