Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.
about
Sds22 and Repo-Man stabilize chromosome segregation by counteracting Aurora B on anaphase kinetochoresMutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfismDepletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatasesA small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora BMaintaining Genome Stability in Defiance of Mitotic DNA DamageUbiquitin-Mediated Degradation of Aurora KinasesThe Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint SignalingReconstituting the kinetochore–microtubule interface: what, why, and howAurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindleRegulatory mechanisms that control mitotic kinesinsRole of the Number of Microtubules in Chromosome Segregation during Cell DivisionSpatial Compartmentalization Specializes the Function of Aurora A and Aurora B.Tale of a multifaceted co-activator, hADA3: from embryogenesis to cancer and beyondChromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubulesChromosome congression is promoted by CENP-Q- and CENP-E-dependent pathways.The human SKA complex drives the metaphase-anaphase cell cycle transition by recruiting protein phosphatase 1 to kinetochoresA Centromere-Signaling Network Underlies the Coordination among Mitotic EventsHuman chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosisEvolutionarily conserved protein ERH controls CENP-E mRNA splicing and is required for the survival of KRAS mutant cancer cellsLoss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips.Cenp-meta is required for sustained spindle checkpointThe MPS1 family of protein kinases.The kinetochoreKinetochore-microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E.CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint.Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21.How chromosome mis-segregation leads to cancer: lessons from BubR1 mouse modelsSensing centromere tension: Aurora B and the regulation of kinetochore function.Temperature-sensitive ipl1-2/Aurora B mutation is suppressed by mutations in TOR complex 1 via the Glc7/PP1 phosphataseThe chromosomal passenger complex (CPC) as a key orchestrator of orderly mitotic exit and cytokinesis.Alisertib, an Aurora kinase A inhibitor, induces apoptosis and autophagy but inhibits epithelial to mesenchymal transition in human epithelial ovarian cancer cellsAurora B dynamics at centromeres create a diffusion-based phosphorylation gradient.Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint.Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.Kinetochore motors drive congression of peripheral polar chromosomes by overcoming random arm-ejection forces.Preventing farnesylation of the dynein adaptor Spindly contributes to the mitotic defects caused by farnesyltransferase inhibitors.Correction of microtubule-kinetochore attachment errors: mechanisms and role in tumor suppression.Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics.
P2860
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P2860
Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.
description
2010 nî lūn-bûn
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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年論文
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2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Aurora kinases and protein pho ...... through regulation of CENP-E.
@ast
Aurora kinases and protein pho ...... through regulation of CENP-E.
@en
Aurora kinases and protein pho ...... through regulation of CENP-E.
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type
label
Aurora kinases and protein pho ...... through regulation of CENP-E.
@ast
Aurora kinases and protein pho ...... through regulation of CENP-E.
@en
Aurora kinases and protein pho ...... through regulation of CENP-E.
@nl
prefLabel
Aurora kinases and protein pho ...... through regulation of CENP-E.
@ast
Aurora kinases and protein pho ...... through regulation of CENP-E.
@en
Aurora kinases and protein pho ...... through regulation of CENP-E.
@nl
P2093
P2860
P1433
P1476
Aurora kinases and protein pho ...... n through regulation of CENP-E
@en
P2093
Andrew J Holland
Weijie Lan
P2860
P304
P356
10.1016/J.CELL.2010.06.039
P407
P577
2010-08-01T00:00:00Z