Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices - Test2 - elhamkhani - TriplyDB

Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices

Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices

http://www.wikidata.org/entity/Q34075070

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Oxidized cholesterol as the driving force behind the development of Alzheimer's disease Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Estrogen: a master regulator of bioenergetic systems in the brain and body Leptin: new hope for the treatment of post-operative cognitive dysfunction?Adipocytokines and CD34 progenitor cells in Alzheimer's disease Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway Oligomeric forms of insulin amyloid aggregation disrupt outgrowth and complexity of neuron-like PC12 cells.Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease.Gadd153 and NF-κB crosstalk regulates 27-hydroxycholesterol-induced increase in BACE1 and β-amyloid production in human neuroblastoma SH-SY5Y cells.Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus.Does the oxysterol 27-hydroxycholesterol underlie Alzheimer's disease-Parkinson's disease overlap?Amyloid-β oligomers induce differential gene expression in adult human brain slices.Obesity, diabetes, and leptin resistance promote tau pathology in a mouse model of disease.Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease.Leptin signaling and Alzheimer's disease.Obesity, leptin, and Alzheimer's disease Adipocyte-derived factors in age-related dementia and their contribution to vascular and Alzheimer pathology Leptin Dysfunction and Alzheimer's Disease: Evidence from Cellular, Animal, and Human Studies.Lipids and adipokines as risk factors for Alzheimer's disease.Relationship between oxysterols and mild cognitive impairment in the elderly: a case-control study Identification of microRNAs involved in Alzheimer's progression using a rabbit model of the disease Neuroglialpharmacology: myelination as a shared mechanism of action of psychotropic treatments.The link between altered cholesterol metabolism and Alzheimer's disease.Are microRNAs the Molecular Link Between Metabolic Syndrome and Alzheimer's Disease?Impact of Insulin Degrading Enzyme and Neprilysin in Alzheimer's Disease Biology: Characterization of Putative Cognates for Therapeutic Applications.Oxidized LDL lipids increase β-amyloid production by SH-SY5Y cells through glutathione depletion and lipid raft formation.Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol.Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway.Method for organotypic tissue culture in the aged animal.Combination treatment with leptin and pioglitazone in a mouse model of Alzheimer's disease.Using redescription mining to relate clinical and biological characteristics of cognitively impaired and Alzheimer's disease patients.Palmitate-induced Endoplasmic Reticulum stress and subsequent C/EBPα Homologous Protein activation attenuates leptin and Insulin-like growth factor 1 expression in the brain.Melatonin Prevents the Harmful Effects of Obesity on the Brain, Including at the Behavioral Level.Maternal low-protein diet decreases brain-derived neurotrophic factor expression in the brains of the neonatal rat offspring.Serum leptin and risk of cognitive decline in elderly italians.Fuzhisan Ameliorates the Memory Deficits in Aged SAMP8 Mice via Decreasing Aβ Production and Tau Hyperphosphorylation of the Hippocampus.Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease.A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.Regulation of Hippocampal Synaptic Function by the Metabolic Hormone, Leptin: Implications for Health and Neurodegenerative Disease

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Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices

http://www.wikidata.org/entity/Q34075070

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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type

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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prefLabel

Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

@en

Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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Journal of Alzheimer's Disease

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Leptin reduces the accumulatio ...... l in rabbit organotypic slices

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P2093

Bhanu Dasari

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Jared Schommer

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Jaya R P Prasanthi

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Othman Ghribi

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P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

Further evidence that the inhibition of glycogen synthase kinase-3beta by IGF-1 is mediated by PDK1/PKB-induced phosphorylation of Ser-9 and not by dephosphorylation of Tyr-216

Leptin regulates tau phosphorylation and amyloid through AMPK in neuronal cells

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme

Differential expression of cholesterol hydroxylases in Alzheimer's disease

Potential mechanisms linking cholesterol to Alzheimer's disease-like pathology in rabbit brain, hippocampal organotypic slices, and skeletal muscle

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.

Leptin: a novel therapeutic strategy for Alzheimer's disease

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1007-1019

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scholarly article

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10.3233/JAD-2010-1298

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3

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19

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Gurdeep Marwarha

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2010-01-01T00:00:00Z

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20157255

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phosphorylation

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2924284

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