Reversible changes in pancreatic islet structure and function produced by elevated blood glucose. - Test2 - elhamkhani - TriplyDB

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.

http://www.wikidata.org/entity/Q34086567

about

Alpha-, Delta- and PP-cells: Are They the Architectural Cornerstones of Islet Structure and Co-ordination?High-content screening identifies a role for Na(+) channels in insulin production A 3D map of the islet routes throughout the healthy human pancreas.Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult mice Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?Combining quantitative 2D and 3D image analysis in the serial block face SEM: application to secretory organelles of pancreatic islet cells.The value of in vitro studies in a case of neonatal diabetes with a novel Kir6.2-W68G mutation.Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes Successful transfer to sulfonylureas in KCNJ11 neonatal diabetes is determined by the mutation and duration of diabetes.A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling Hyperglycaemia induces metabolic dysfunction and glycogen accumulation in pancreatic β-cells.PAX6 maintains β cell identity by repressing genes of alternative islet cell types.Metabolic Stress and Compromised Identity of Pancreatic Beta Cells.Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.Functional identification of islet cell types by electrophysiological fingerprinting.Islet α cells and glucagon--critical regulators of energy homeostasis.Stem cells versus plasticity in liver and pancreas regeneration.Stress-induced adaptive islet cell identity changes β-cell differentiation status in type 2 diabetes.Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.β-Cell dysfunction in diabetes: a crisis of identity?Pancreatic β-cell identity in diabetes.The undoing and redoing of the diabetic β-cell.Neonatal Diabetes and the KATP Channel: From Mutation to Therapy.Sustained zero-order delivery of GC-1 from a nanochannel membrane device alleviates metabolic syndrome.Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment.Picroside II Shows Protective Functions for Severe Acute Pancreatitis in Rats by Preventing NF-κB-Dependent Autophagy.Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance.Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes Mouse insulin cells expressing an inducible RIPCre transgene are functionally impaired.The mammal-specific Pdx1 Area II enhancer has multiple essential functions in early endocrine cell specification and postnatal β-cell maturation.Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes.Antidiabetic drug glyburide modulates depressive-like behavior comorbid with insulin resistance.Nrf2/antioxidant pathway mediates β cell self-repair after damage by high-fat diet-induced oxidative stress.Pancreatic β-Cell Electrical Activity and Insulin Secretion: Of Mice and Men.Preservation of Reduced Numbers of Insulin-Positive Cells in Sulfonylurea-Unresponsive KCNJ11-Related Diabetes.

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P2860

Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.

http://www.wikidata.org/entity/Q34086567

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

name

Reversible changes in pancreat ...... ced by elevated blood glucose.

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Reversible changes in pancreat ...... ced by elevated blood glucose.

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Reversible changes in pancreat ...... ced by elevated blood glucose.

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type

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Reversible changes in pancreat ...... ced by elevated blood glucose.

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Reversible changes in pancreat ...... ced by elevated blood glucose.

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Reversible changes in pancreat ...... ced by elevated blood glucose.

@nl

prefLabel

Reversible changes in pancreat ...... ced by elevated blood glucose.

@ast

Reversible changes in pancreat ...... ced by elevated blood glucose.

@en

Reversible changes in pancreat ...... ced by elevated blood glucose.

@nl

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Nature Communications

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Reversible changes in pancreat ...... ced by elevated blood glucose.

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Alice E Adriaenssens

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Anne Clark

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Frances M Ashcroft

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Katia K Mattis

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Kenju Shimomura

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Melissa F Brereton

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Michaela Iberl

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Peter Proks

http://www.w3.org/2001/XMLSchema#string

Quan Zhang

http://www.w3.org/2001/XMLSchema#string

William Dace

http://www.w3.org/2001/XMLSchema#string

P2860

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

Influence of diabetes on the loss of beta cell differentiation after islet transplantation in rats

R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion

Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

Critical reduction in beta-cell mass results in two distinct outcomes over time. Adaptation with impaired glucose tolerance or decompensated diabetes.

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.

Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.

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4639

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10.1038/NCOMMS5639

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5

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Ioannis Spiliotis

Fiona M Gribble

Reshma D Ramracheya

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2014-08-22T00:00:00Z

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264986494

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1032967356

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25145789

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4143961

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