Natural products version 2.0: connecting genes to molecules. - Test2 - elhamkhani - TriplyDB

Natural products version 2.0: connecting genes to molecules.

Natural products version 2.0: connecting genes to molecules.

http://www.wikidata.org/entity/Q34096062

about

Metabolic reconstruction for metagenomic data and its application to the human microbiome Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity Systems Biology Approaches to Understand Natural Products Biosynthesis Synthetic biology for pharmaceutical drug discovery Leveraging structure for enzyme function prediction: methods, opportunities, and challenges Synthetic biology of antimicrobial discovery Crystal structure of SsfS6, the putativeC-glycosyltransferase involved in SF2575 biosynthesis The O-carbamoyltransferase TobZ catalyzes an ancient enzymatic reaction Heterologous expression and structural characterisation of a pyrazinone natural product assembly line Next-generation sequencing approach for connecting secondary metabolites to biosynthetic gene clusters in fungi Variation in tropical reef symbiont metagenomes defined by secondary metabolism Expanding our understanding of sequence-function relationships of type II polyketide biosynthetic gene clusters: bioinformatics-guided identification of Frankiamicin A from Frankia sp. EAN1pec The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life Crystal ball - 2011 Endless Resistance. Endless Antibiotics?Parallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization.Mass spectrometry tools and workflows for revealing microbial chemistry.Imaging mass spectrometry and genome mining via short sequence tagging identified the anti-infective agent arylomycin in Streptomyces roseosporus Genome mining in Streptomyces avermitilis: cloning and characterization of SAV_76, the synthase for a new sesquiterpene, avermitilol Hassallidins, antifungal glycolipopeptides, are widespread among cyanobacteria and are the end-product of a nonribosomal pathway Metabolic potential of endophytic bacteria.Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli.Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins.Catalysis at the intersection of biology, chemistry, and medicine.Genome mining in Streptomyces clavuligerus: expression and biochemical characterization of two new cryptic sesquiterpene synthases.Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination.Examining the fish microbiome: vertebrate-derived bacteria as an environmental niche for the discovery of unique marine natural products.Microscale methodology for structure elucidation of natural products.Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis Prospecting genomes for lasso peptides.IMG 4 version of the integrated microbial genomes comparative analysis system.Strain prioritization for natural product discovery by a high-throughput real-time PCR method.Bioactive natural products from Papua New Guinea marine sponges.A chemical ecogenomics approach to understand the roles of secondary metabolites in fungal cereal pathogens.Practical 4'-phosphopantetheine active site discovery from proteomic samples.21st century natural product research and drug development and traditional medicines Deep sequencing of non-ribosomal peptide synthetases and polyketide synthases from the microbiomes of Australian marine sponges.Engineering polyketide synthases and nonribosomal peptide synthetases.

P2860

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P2860

Natural products version 2.0: connecting genes to molecules.

http://www.wikidata.org/entity/Q34096062

description

2010 nî lūn-bûn

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2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Natural products version 2.0: connecting genes to molecules.

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Natural products version 2.0: connecting genes to molecules.

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Natural products version 2.0: connecting genes to molecules.

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Journal of the American Chemical Society

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Natural products version 2.0: connecting genes to molecules

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Christopher T Walsh

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P2860

High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites

Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

Taxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenase

The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin

Selective interaction between nonribosomal peptide synthetases is facilitated by short communication-mediating domains

Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme

Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis

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2469-2493

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Michael A. Fischbach

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