Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis - Test2 - elhamkhani - TriplyDB

Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

http://www.wikidata.org/entity/Q34098843

about

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response Cloning, expression, characterization, and role in autocrine cell growth of cell surface retention sequence binding protein-1.Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantation Heparanase and hepatocellular carcinoma: promoter or inhibitor?Regulation of intracellular signaling by extracellular glycan remodeling.Isomalto oligosaccharide sulfate inhibits tumor growth and metastasis of hepatocellular carcinoma in nude mice.CXCL7-Mediated Stimulation of Lymphangiogenic Factors VEGF-C, VEGF-D in Human Breast Cancer Cells Adaptive evolution of heparanase in hypoxia-tolerant Spalax: gene cloning and identification of a unique splice variant.Dissociation between mature phenotype and impaired transmigration in dendritic cells from heparanase-deficient mice.Structural characterization of human heparanase reveals insights into substrate recognition.Role of endothelial heparanase in delayed-type hypersensitivity.PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models Mammalian heparanase: what is the message?The role of heparanase in lymph node metastatic dissemination: dynamic contrast-enhanced MRI of Eb lymphoma in mice.In vitro and ex vivo evaluation of a multi-epitope heparinase vaccine for various malignancies.FGF2 binding, signaling, and angiogenesis are modulated by heparanase in metastatic melanoma cells Halofuginone inhibits angiogenesis and growth in implanted metastatic rat brain tumor model--an MRI study Preclinical studies in support of defibrotide for the treatment of multiple myeloma and other neoplasias Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.Heparanase localization and expression by head and neck cancer: correlation with tumor progression and patient survival The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus.Heparanase as a molecular target of cancer chemotherapy.Gekko-sulfated glycopeptide inhibits tumor angiogenesis by targeting basic fibroblast growth factor Hypoxic stress and cancer: imaging the axis of evil in tumor metastasis.Heparanase: a target for drug discovery in cancer and inflammation.Fucoidan inhibits the growth of hepatocellular carcinoma independent of angiogenesis.The antineoplastic effect of low-molecular-weight heparins - a literature review Enzymatic function of multiple origins regulates the progression of colorectal cancer and the development of metastases.An experimental platform for studying growth and invasiveness of tumor cells within teratomas derived from human embryonic stem cells Alternatively spliced Spalax heparanase inhibits extracellular matrix degradation, tumor growth, and metastasis Inverse correlation between HPSE gene single nucleotide polymorphisms and heparanase expression: possibility of multiple levels of heparanase regulation.Oligomannurarate sulfate blocks tumor growth by inhibiting NF-kappaB activation A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.Analysis on regulatory network linked to Hpa gene in invasion and metastasis of colon cancer Construction of specific magnetic resonance imaging/optical dual-modality molecular probe used for imaging angiogenesis of gastric cancer.Characterization of HPSE gene single nucleotide polymorphisms in Jewish populations of Israel.Matrine inhibits invasiveness and metastasis of human malignant melanoma cell line A375 in vitro.Cellular uptake of mammalian heparanase precursor involves low density lipoprotein receptor-related proteins, mannose 6-phosphate receptors, and heparan sulfate proteoglycans.

P2860

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P2860

Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

http://www.wikidata.org/entity/Q34098843

description

2002 nî lūn-bûn

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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

Cell surface expression and se ...... or angiogenesis and metastasis

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Cell surface expression and se ...... or angiogenesis and metastasis

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Cell surface expression and se ...... or angiogenesis and metastasis

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type

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Cell surface expression and se ...... or angiogenesis and metastasis

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Cell surface expression and se ...... or angiogenesis and metastasis

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Cell surface expression and se ...... or angiogenesis and metastasis

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prefLabel

Cell surface expression and se ...... or angiogenesis and metastasis

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Cell surface expression and se ...... or angiogenesis and metastasis

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Cell surface expression and se ...... or angiogenesis and metastasis

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Proceedings of the National Academy of Sciences of the United States of America

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Cell surface expression and se ...... or angiogenesis and metastasis

@en

P2093

Eduardo Mitrani

http://www.w3.org/2001/XMLSchema#string

Eyal Zcharia

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Helena Aingorn

http://www.w3.org/2001/XMLSchema#string

Israel Vlodavsky

http://www.w3.org/2001/XMLSchema#string

Orit Goldshmidt

http://www.w3.org/2001/XMLSchema#string

Rinat Abramovitch

http://www.w3.org/2001/XMLSchema#string

Shula Metzger

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Volker Schirrmacher

http://www.w3.org/2001/XMLSchema#string

Yael Friedmann

http://www.w3.org/2001/XMLSchema#string

P2860

Human heparanase. Purification, characterization, cloning, and expression

Mammalian heparanase: gene cloning, expression and function in tumor progression and metastasis

Cloning of mammalian heparanase, an important enzyme in tumor invasion and metastasis

Cloning and functional expression of a human heparanase gene

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

Expression of heparanase, Mdm2, and erbB2 in ovarian cancer

Heparanase expression in primary and metastatic pancreatic cancer

Molecular properties and involvement of heparanase in cancer progression and mammary gland morphogenesis

Integral membrane heparan sulfate proteoglycans

Matrix proteoglycans: from molecular design to cellular function

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10031-10036

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scholarly article

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10.1073/PNAS.152070599

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15

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99

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2002-07-03T00:00:00Z

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11277722

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12097647

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126619

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