The molecular pharmacology of CGRP and related peptide receptor subtypes.
about
Calcitonin gene-related peptide (CGRP) receptor antagonists in the treatment of migraineCalcitonin gene-related peptide: key regulator of cutaneous immunityCGRP receptors mediating CGRP-, adrenomedullin- and amylin-induced relaxation in porcine coronary arteries. Characterization with 'Compound 1' (WO98/11128), a non-peptide antagonistCloning, characterization and central nervous system distribution of receptor activity modifying proteins in the ratUpregulation of adrenomedullin and its receptor components during cardiomyocyte hypertrophy induced by chronic inhibition of nitric oxide synthesis in ratsVariable sensitivity to noxious heat is mediated by differential expression of the CGRP geneHydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor geneFunctional expression of heteromeric calcitonin gene-related peptide and adrenomedullin receptors in yeast.Evidence of a role for NK1 and CGRP receptors in mediating neurogenic vasodilatation in the mouse ear.The vasorelaxant effect of adrenomedullin, proadrenomedullin N-terminal 20 peptide and amylin in human skin.Amylin receptor agonists: a novel pharmacological approach in the management of insulin-treated diabetes mellitus.Effects of the CGRP receptor antagonist BIBN4096BS on capsaicin-induced carotid haemodynamic changes in anaesthetised pigsCalcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic mucosa via myenteric neurons and tachykinin NK2/NK3 receptors.Noncompetitive antagonism of BIBN4096BS on CGRP-induced responses in human subcutaneous arteriesIncreased alphaCGRP potency and CGRP-receptor antagonist affinity in isolated hypoxic porcine intramyocardial arteries.A role for adrenomedullin as a pain-related peptide in the ratCharacterization and effects on cAMP accumulation of adrenomedullin and calcitonin gene-related peptide (CGRP) receptors in dissociated rat spinal cord cell culture.Development of anti-migraine therapeutics using the capsaicin-induced dermal blood flow model.Vascular actions of calcitonin gene-related peptide and adrenomedullin.The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.What makes a CGRP2 receptor?Brainstem neuropeptides and vagal protection of the gastric mucosal against injury: role of prostaglandins, nitric oxide and calcitonin-gene related peptide in capsaicin afferentsInhibition of calcitonin gene-related peptide function: a promising strategy for treating migraineDiabetic neuropathy and heart failure: role of neuropeptides.Evidence for CGRP re-uptake in rat dura mater encephali.Receptor activity-modifying protein 1 increases baroreflex sensitivity and attenuates Angiotensin-induced hypertension.A comparison of the actions of BIBN4096BS and CGRP(8-37) on CGRP and adrenomedullin receptors expressed on SK-N-MC, L6, Col 29 and Rat 2 cells.CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS.Targeted blocking of gene expression for CGRP receptors elevates pulmonary artery pressure in hypoxic rats.The immunohistochemical expression of calcitonin receptor-like receptor (CRLR) in human gliomas.Evidence that post-tetanic potentiation is mediated by neuropeptide release in Aplysia.Enhanced vasodilator responses to calcitonin gene-related peptide (CGRP) in subcutaneous arteries in human hypertension.Effects of pramlintide, an amylin analogue, on gastric emptying in type 1 and 2 diabetes mellitus.Human osteoblast-like cell proliferation induced by calcitonin-related peptides involves PKC activity.Calcitonin gene related peptide and N-procalcitonin modulate CD11b upregulation in lipopolysaccharide activated monocytes and neutrophils.Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: Results of the Phase 1 program.Role of calcitonin gene-related peptide in energy metabolism.Loss of alpha CGRP reduces sound-evoked activity in the cochlear nerve.Calcitonin gene-related peptide (CGRP) may award relative protection from interferon-γ-induced collapse of human hair follicle immune privilege.RAMP1 suppresses mucosal injury from dextran sodium sulfate-induced colitis in mice.
P2860
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P2860
The molecular pharmacology of CGRP and related peptide receptor subtypes.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@ast
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@en
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@nl
type
label
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@ast
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@en
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@nl
prefLabel
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@ast
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@en
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@nl
P2093
P1476
The molecular pharmacology of CGRP and related peptide receptor subtypes.
@en
P2093
P304
P356
10.1016/S0165-6147(00)01555-8
P577
2000-11-01T00:00:00Z