Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function

Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function

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http://www.wikidata.org/entity/Q34115273
Krüppel-like factor 6 is a co-activator of NF-κB that mediates p65-dependent transcription of selected downstream genesAh Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-MotifsKrüppel-like factor 6 expression changes during trophoblast syncytialization and transactivates ßhCG and PSG placental genes.KLF6 depletion promotes NF-κB signaling in glioblastoma.Differential splicing alters subcellular localization of the alpha but not beta isoform of the MIER1 transcriptional regulator in breast cancer cells.KLF6 loss of function in human prostate cancer progression is implicated in resistance to androgen deprivation.The reproductive phenotype of mice null for transcription factor Krüppel-like factor 13 suggests compensatory function of family member Krüppel-like factor 9 in the peri-implantation uterusKrüppel-like Factor 7 engineered for transcriptional activation promotes axon regeneration in the adult corticospinal tract.Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing.The tumor suppressor Kruppel-like factor 6 is a novel aryl hydrocarbon receptor DNA binding partner.GSK3β phosphorylation of the KLF6 tumor suppressor promotes its transactivation of p21.The Role of the 3' Untranslated Region in the Post-Transcriptional Regulation of KLF6 Gene Expression in Hepatocellular CarcinomaKrüppel-like factors in mammalian stem cells and development.The conserved basic residues and the charged amino acid residues at the α-helix of the zinc finger motif regulate the nuclear transport activity of triple C2H2 zinc finger proteins.Krüppel-like factors: Crippling and un-crippling metabolic pathways.Nuclear Klf4 accumulation is associated with cetuximab drug-resistance and predicts poor prognosis of nasopharyngeal carcinoma.
P2860

Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6 (KLF6) protein stability and tumor suppressor function

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http://www.wikidata.org/entity/Q34115273
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2010 nî lūn-bûn
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2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
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name
Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@ast
Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@en
Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6
@nl
type
label
Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@ast
Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@en
Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6
@nl
prefLabel
Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@ast
Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@en
Nucleo-cytoplasmic localization domains regulate Krüppel-like factor 6
@nl
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Nucleo-cytoplasmic localizatio ...... and tumor suppressor function
@en
P2093
P2860
P31
P356
10.1371/JOURNAL.PONE.0012639
P407
P433
P478
P50
P577
P5875
P698
P932