Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.
about
RNA-binding proteins in eye development and disease: implication of conserved RNA granule componentsExpression Atlas of the Deubiquitinating Enzymes in the Adult Mouse Retina, Their Evolutionary Diversification and Phenotypic RolesPrp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.Regulation of a novel isoform of Receptor Expression Enhancing Protein REEP6 in rod photoreceptors by bZIP transcription factor NRLMutations in spliceosomal proteins and retina degenerationTemporal and tissue specific regulation of RP-associated splicing factor genes PRPF3, PRPF31 and PRPC8--implications in the pathogenesis of RP.Alternative splicing and retinal degenerationMutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.Dynamics of regulatory networks in the developing mouse retina.PRPF mutations are associated with generalized defects in spliceosome formation and pre-mRNA splicing in patients with retinitis pigmentosa.A Study into the Evolutionary Divergence of the Core Promoter Elements of PRPF31 and TFPT.Mutant Prpf31 causes pre-mRNA splicing defects and rod photoreceptor cell degeneration in a zebrafish model for Retinitis pigmentosa.RNA-Seq: Improving Our Understanding of Retinal Biology and Disease.Mislocalisation of BEST1 in iPSC-derived retinal pigment epithelial cells from a family with autosomal dominant vitreoretinochoroidopathy (ADVIRC)Targeted RP9 ablation and mutagenesis in mouse photoreceptor cells by CRISPR-Cas9.Dynamic lineage analysis of embryonic morphogenesis using transgenic quail and 4D multispectral imaging.Deubiquitylases from genes to organism.Characterization of lincRNA expression in the human retinal pigment epithelium and differentiated induced pluripotent stem cells.Reverse Nearest Neighbor Search on a Protein-Protein Interaction Network to Infer Protein-Disease AssociationsVariability in clinical phenotypes of PRPF8-linked autosomal dominant retinitis pigmentosa correlates with differential PRPF8/SNRNP200 interactions.Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosaFormation of 53BP1 foci and ATM activation under oxidative stress is facilitated by RNA:DNA hybrids and loss of ATM-53BP1 expression promotes photoreceptor cell survival in mice
P2860
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P2860
Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.
description
2011 nî lūn-bûn
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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
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2011年論文
@zh-tw
2011年论文
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name
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@ast
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en-gb
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@nl
type
label
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@ast
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en-gb
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@nl
prefLabel
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@ast
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en-gb
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@nl
P2093
P2860
P50
P356
P1476
Three gene-targeted mouse mode ...... RPE and retinal degeneration.
@en
P2093
Bertrand M Deramaudt
Emeline F Nandrot
John J Graziotto
Michael H Farkas
Shomi S Bhattacharya
P2860
P304
P356
10.1167/IOVS.10-5194
P407
P577
2011-01-05T00:00:00Z