Prp8 protein: at the heart of the spliceosome - Test2 - elhamkhani - TriplyDB

Prp8 protein: at the heart of the spliceosome

Prp8 protein: at the heart of the spliceosome

http://www.wikidata.org/entity/Q24537373

about

Nucleomorph genome sequence of the cryptophyte alga Chroomonas mesostigmatica CCMP1168 reveals lineage-specific gene loss and genome complexity Identification, cloning, and functional analysis of the human U6 snRNA-specific terminal uridylyl transferase Cwc2 and its human homologue RBM22 promote an active conformation of the spliceosome catalytic centre Prp8p dissection reveals domain structure and protein interaction sites.The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP CryoEM structures of two spliceosomal complexes: starter and dessert at the spliceosome feast Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process Erbb2 is required for cardiac atrial electrical activity during development Crystal structure of the C-terminal domain of splicing factor Prp8 carrying retinitis pigmentosa mutants X-ray Structures of U2 snRNA−Branchpoint Duplexes Containing Conserved Pseudouridines † ‡Crystal structure of the -finger domain of Prp8 reveals analogy to ribosomal proteins Structure and function of an RNase H domain at the heart of the spliceosome Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2 Mechanism for Aar2p function as a U5 snRNP assembly factor Crystal structure of Prp8 reveals active site cavity of the spliceosome Structural basis for dual roles of Aar2p in U5 snRNP assembly A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation Structure of a yeast spliceosome at 3.6-angstrom resolution Molecular architecture of the human U4/U6.U5 tri-snRNP Structure of a yeast catalytic step I spliceosome at 3.4 Å resolution Molecular architecture of the Saccharomyces cerevisiae activated spliceosome Cwc23, an essential J protein critical for pre-mRNA splicing with a dispensable J domain Yeast ntr1/spp382 mediates prp43 function in postspliceosomes.Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain.Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.Inhibition of a spliceosome turnover pathway suppresses splicing defects.The Isy1p component of the NineTeen complex interacts with the ATPase Prp16p to regulate the fidelity of pre-mRNA splicing.Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation Functional interactions between Prp8, Prp18, Slu7, and U5 snRNA during the second step of pre-mRNA splicing.prp8 mutations that cause human retinitis pigmentosa lead to a U5 snRNP maturation defect in yeast A homolog of lariat-debranching enzyme modulates turnover of branched RNA.Dynamic Contacts of U2, RES, Cwc25, Prp8 and Prp45 Proteins with the Pre-mRNA Branch-Site and 3' Splice Site during Catalytic Activation and Step 1 Catalysis in Yeast Spliceosomes.Prp8 retinitis pigmentosa mutants cause defects in the transition between the catalytic steps of splicing.Rapid screening of yeast mutants with reporters identifies new splicing phenotypes.CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome.Molecular dissection of step 2 catalysis of yeast pre-mRNA splicing investigated in a purified system.A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300.A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle Progression Pattern dynamics in adaxial-abaxial specific gene expression are modulated by a plastid retrograde signal during Arabidopsis thaliana leaf development Unexpected role of the steroid-deficiency protein ecdysoneless in pre-mRNA splicing

P2860

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P2860

Prp8 protein: at the heart of the spliceosome

http://www.wikidata.org/entity/Q24537373

description

2005 nî lūn-bûn

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2005 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2005 թվականի մայիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Prp8 protein: at the heart of the spliceosome

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Jean D Beggs

http://www.w3.org/2001/XMLSchema#string

Richard J Grainger

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P2860

JAMM: a metalloprotease-like zinc site in the proteasome and signalosome

MPN+, a putative catalytic motif found in a subset of MPN domain proteins from eukaryotes and prokaryotes, is critical for Rpn11 function

The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein

A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing

Nuclear speckles: a model for nuclear organelles

Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi

The highly reduced genome of an enslaved algal nucleus

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

U box proteins as a new family of ubiquitin-protein ligases

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription

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533-557

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scholarly article

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5038081

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10.1261/RNA.2220705

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15840809

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