Determinants of metabotropic glutamate receptor-5-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration.
about
The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cellsFine tuning of cytosolic Ca (2+) oscillationsOptogenetic Glia Manipulation: Possibilities and Future ProspectsThe regulation of M1 muscarinic acetylcholine receptor desensitization by synaptic activity in cultured hippocampal neuronsN-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neuronsIP3 3-kinase opposes NGF driven neurite outgrowthUse of Fluorescence Resonance Energy Transfer-based Biosensors for the Quantitative Analysis of Inositol 1,4,5-Trisphosphate Dynamics in Calcium OscillationsBidirectional Hebbian plasticity at hippocampal mossy fiber synapses on CA3 interneurons.Connexin 43 hemichannels contribute to cytoplasmic Ca2+ oscillations by providing a bimodal Ca2+-dependent Ca2+ entry pathway.Live cell imaging with protein domains capable of recognizing phosphatidylinositol 4,5-bisphosphate; a comparative study.Isoform-specific phosphorylation of metabotropic glutamate receptor 5 by protein kinase C (PKC) blocks Ca2+ oscillation and oscillatory translocation of Ca2+-dependent PKC.Differential binding of calmodulin to group I metabotropic glutamate receptors regulates receptor trafficking and signaling.New concepts in calcium-sensing receptor pharmacology and signallingHigh Cell Density Upregulates Calcium Oscillation by Increasing Calcium Store Content via Basal Mitogen-Activated Protein Kinase ActivityDefining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.Investigating metabotropic glutamate receptor 5 allosteric modulator cooperativity, affinity, and agonism: enriching structure-function studies and structure-activity relationships.Calmodulin dynamically regulates the trafficking of the metabotropic glutamate receptor mGluR5.Spatiotemporal organization of Ca dynamics: a modeling-based approach.mGluRs modulate strength and timing of excitatory transmission in hippocampal area CA3.Inositol 1,4,5-trisphosphate receptor-mediated calcium release in Purkinje cells: from molecular mechanism to behavior.Modeling the intracellular organization of calcium signaling.Acetylcholine evokes an InsP3R1-dependent transient Ca2+ signal in rat duodenum myocytes.Metabotropic glutamate receptor subtype 5: molecular pharmacology, allosteric modulation and stimulus biasDefining protein kinase/phosphatase isoenzymic regulation of mGlu₅ receptor-stimulated phospholipase C and Ca²⁺ responses in astrocytes.Reproducibility and Comparability of Computational Models for Astrocyte Calcium Excitability.Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cellsEffects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor.Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons.Spatiotemporal characteristics of calcium dynamics in astrocytes.A crucial role for cAMP and protein kinase A in D1 dopamine receptor regulated intracellular calcium transients.PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes.Increased receptor stimulation elicits differential calcium-sensing receptor(T888) dephosphorylation.A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing.Single cell analysis and temporal profiling of agonist-mediated inositol 1,4,5-trisphosphate, Ca2+, diacylglycerol, and protein kinase C signaling using fluorescent biosensors.Quantitative analysis reveals multiple mechanisms of allosteric modulation of the mGlu5 receptor in rat astroglia.Group I mGluR-induced epileptogenesis: distinct and overlapping roles of mGluR1 and mGluR5 and implications for antiepileptic drug design.Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals.Role of Ca2+ feedback on single cell inositol 1,4,5-trisphosphate oscillations mediated by G-protein-coupled receptors.An allosteric modulator to control endogenous G protein-coupled receptors with light.Altered agonist sensitivity and desensitization of neuronal mGluR1 responses in knock-in mice by a single amino acid substitution at the PKC phosphorylation site.
P2860
Q24530164-21488E25-8FDA-4969-80AB-1C9F640462EBQ28072046-75520091-4956-41AD-9EF9-C494FF782A72Q28080317-F814E442-A188-41FC-9AF4-85CD16B6B635Q28577190-8134623A-B981-46E5-BF9A-CCFE8087A989Q28594380-147085BC-43D9-4903-933D-CED170A9A3DCQ28731851-A3F96E2D-BCAB-4528-A4CB-D21610E1F97DQ30486613-B7004848-AB1C-4DAF-86B0-0D51320DD2F3Q30486639-EDDCDCDD-BE20-4909-9AEF-7AF1F812E920Q30512751-B62690C8-B4A5-4659-A7A0-8B55496D4BFBQ33505455-B582CB30-ECE9-4BE5-8B14-5ED271A42BC3Q34270273-F95DFF74-9ED1-4ED1-BFE7-E61C0BD8B735Q35034819-523C85A2-A43E-427E-A69A-ABFBE06DCE4AQ35657894-C6DB1910-668D-46A2-B156-DA8466006C20Q35785014-F25A15AE-2DEC-43E6-B0B5-E2D2484E7DDAQ35916711-9505B9BC-5B49-4770-9B2E-FBCE88B9FC3CQ36335613-EEE227E1-2ABA-4FA5-8B3D-96AFCEA496F2Q36858682-564DA4C3-CDF0-46B5-A54D-7074A1B193B0Q37795557-625FD289-8CE0-41A9-A01D-69455B84766AQ37874147-4C773A8E-4237-450A-880B-DCF5470CBABFQ37893988-45C0BFFD-156A-42C2-8495-76D379583277Q38194101-216AC57D-4049-47B4-A098-2353D538071EQ38287893-67037373-7A84-4550-8631-14B4F7619156Q38567309-879961A1-21D1-49F0-AC2D-0AF412A22A3FQ38649735-FE9EA27A-1AD0-49BB-A150-97F38C52A667Q38922212-3C2C4551-749D-4B81-9797-F2C87380089FQ39729997-3737AC2E-EFE5-4DC2-913C-91C7898BEB41Q39802146-D66F8E95-FC9C-44E5-9436-14436ABEBCE5Q39956037-FC7A5E6C-844A-4241-9E2C-2453210CD777Q39971841-92C2A1AF-BCA6-418C-9DBB-D62FD6BF0DF5Q40016154-FE750E94-2A63-4013-820B-9A714201BFB3Q40305310-5418C4C9-DC63-4831-888E-2A80D23FEC90Q40318883-68B96E30-78C7-48CF-96BA-4FB074E61276Q40423815-7CEB108B-EB4A-4FA9-BF8F-8FA9A867AB41Q40443128-D6C969DD-DAB0-4E44-AE27-CF798D3566CAQ41864251-DF208A1A-068E-41FE-8334-922BE9B5FEB5Q42139378-04325482-E80B-4AC8-8A42-56E1362EAD9BQ42327808-1B1F3CA7-016B-477A-B7EF-4BDB082B6F8EQ42439150-21EC0E39-8DD6-40D2-97A5-CBF7043136CFQ42704321-40420539-FC46-4110-8DBC-6D8B613111E7Q45014662-0D5B97C9-8AFD-4263-B5C4-0669EAFC48F3
P2860
Determinants of metabotropic glutamate receptor-5-mediated Ca2+ and inositol 1,4,5-trisphosphate oscillation frequency. Receptor density versus agonist concentration.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Determinants of metabotropic g ...... versus agonist concentration.
@ast
Determinants of metabotropic g ...... versus agonist concentration.
@en
Determinants of metabotropic g ...... versus agonist concentration.
@nl
type
label
Determinants of metabotropic g ...... versus agonist concentration.
@ast
Determinants of metabotropic g ...... versus agonist concentration.
@en
Determinants of metabotropic g ...... versus agonist concentration.
@nl
prefLabel
Determinants of metabotropic g ...... versus agonist concentration.
@ast
Determinants of metabotropic g ...... versus agonist concentration.
@en
Determinants of metabotropic g ...... versus agonist concentration.
@nl
P2093
P2860
P356
P1476
Determinants of metabotropic g ...... versus agonist concentration.
@en
P2093
Mark S Nash
Michael J Schell
Neil R Johnston
Peter J Atkinson
R A John Challiss
Stefan R Nahorski
P2860
P304
35947-35960
P356
10.1074/JBC.M205622200
P407
P577
2002-07-15T00:00:00Z