Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

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http://www.wikidata.org/entity/Q34140579
PGC-1α, mitochondrial dysfunction, and Huntington's diseaseImpaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtinPPARγ as a therapeutic target to rescue mitochondrial function in neurological diseaseHdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid AccumulationEarly deficits in glycolysis are specific to striatal neurons from a rat model of huntington disease.Untargeted metabolic profiling identifies interactions between Huntington's disease and neuronal manganese statusPPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically.Neuroprotective effects of PPAR-γ agonist rosiglitazone in N171-82Q mouse model of Huntington's disease.Mitochondrial permeability transition pore induces mitochondria injury in Huntington disease.Rosiglitazone regulates anti-inflammation and growth inhibition via PTEN.Prospects for neuroprotective therapies in prodromal Huntington's disease.Sulforaphane induces autophagy through ERK activation in neuronal cells.Bcl-2/adenovirus E1B 19-kDa interacting protein (BNip3) has a key role in the mitochondrial dysfunction induced by mutant huntingtin.
P2860

Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.

Item
http://www.wikidata.org/entity/Q34140579
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2012 nî lūn-bûn
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2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
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2012年論文
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2012年论文
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name
Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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type
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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Metabolic state determines sen ...... zation by activation of PPARγ.
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10.1371/JOURNAL.PONE.0030406
P407
P433
P478
P577
P5875
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P921
P932