Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi - Test2 - elhamkhani - TriplyDB

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

http://www.wikidata.org/entity/Q24292161

about

Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death Huntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterations HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction Endoplasmic reticulum stress: cell life and death decisions.Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1 Defining the role of the Bcl-2 family proteins in Huntington's disease Cilia/Ift protein and motor -related bone diseases and mouse models Role of apoptosis in disease Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Genetics and neuropathology of Huntington's disease Huntingtin's function in axonal transport is conserved in Drosophila melanogaster Crystal Structure at 2.8 Å of the DLLRKN-containing Coiled-coil Domain of Huntingtin-interacting Protein 1 (HIP1) Reveals a Surface Suitable for Clathrin Light Chain Binding Crystal Structure at 2.8 Å of Huntingtin-Interacting Protein 1 (HIP1) Coiled-Coil Domain Reveals a Charged Surface Suitable for HIP1 Protein Interactor (HIPPI)Accommodation of structural rearrangements in the huntingtin-interacting protein 1 coiled-coil domain The intraflagellar transport machinery of Chlamydomonas reinhardtii.Architecture and function of IFT complex proteins in ciliogenesis Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain Structural definition of the F-actin-binding THATCH domain from HIP1R IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory cilia Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival Normal huntingtin function: an alternative approach to Huntington's disease Huntington's disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription Vhlh gene deletion induces Hif-1-mediated cell death in thymocytes Hippi is essential for node cilia assembly and Sonic hedgehog signaling Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse The vertebrate primary cilium in development, homeostasis, and disease Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities Is Huntingtin Dispensable in the Adult Brain?Formation and toxicity of soluble polyglutamine oligomers in living cells.Structure and activity of putative intronic miRNA promoters Striatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa.Genome wide gene expression regulation by HIP1 Protein Interactor, HIPPI: prediction and validation Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ.Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14.MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells.The domains of apoptosis: a genomics perspective.

P2860

387faeb0d6ef60112540c48df30529a47a39b696 67f4c92a15de7d4c43096c5064c4990eac2e869d 84b099dab79a1e075c2dbb1fbd53737a2a7aabf2 87f167a3b739356fb402f471c14dc15a2b9fb3a5 94ab00c25319b1b891751b3db92f4dc0abda41ce af759163f19759f4f2d45aefd8366fa98ec738ba bcb998cf2d3239d2933f627bb4e6264a63c79502 bd8b436d80999fa2fa5ccb417a70748a5de764d6 dc95e249067562df0fa0fc44b78111b951737775 eeb1c1c34d289f5035fcfc70021c2fa29133a626

P248

Q24294333-059E3551-9333-4034-AAE5-68B12281B721 Q24303436-28493FD6-DF79-4108-B374-123499592E4E Q24305412-DCB1FB21-A290-4CE0-AAA3-9C3665EBFDCB Q24320479-6B1DD4E1-0812-4AD9-A686-F4E1FAAE4DAB Q24536108-567404AE-5077-4D68-B6C5-4DDB60FC45AC Q24656169-C4874DDE-124B-476B-B4EE-4B01A0592B2E Q26822846-777C737C-0C42-4977-A66B-429BEEFF0A03 Q26865112-08F1BC5A-5831-44D4-B497-D5ECBA92658A Q26865637-C76562D2-BDFD-4888-ADEC-E58FA77B150D Q27005950-A5D84024-A373-4277-8162-33186B906641 Q27023050-C97EFE08-1813-41B7-A5DC-BDECEB73A5E8 Q27331461-154550D6-6FE2-498C-9F3F-BD34C0BB540C Q27643670-C8C7A5C2-A28E-4D44-BA58-C7D7E8DE9A8F Q27649395-69C852E0-BC38-452F-9BCA-E86B3A7AA14E Q27660034-C312DD63-0119-48F6-999D-9561D66D8918 Q27919639-E28CF10E-A292-415A-ABC0-D216154F0B3D Q28000079-72EA32B4-3F72-4DF8-85CA-D92424680D7C Q28115765-D0979572-C60B-4DF6-AE45-7316628CE8A5 Q28119195-8CAB1541-D87A-48E3-B62A-DC665F84B1B9 Q28181491-DB778A2A-E11C-4591-8C7E-328C7A2017DD Q28217008-22EA7C2A-689B-455F-83E3-9DB58A49518E Q28281904-C72DDAE9-3168-485A-BD06-1BFD77DCF06C Q28287646-0819D89D-387B-479C-BE07-8D7F4FCAAFB0 Q28504459-D605E78C-87FA-4896-A7CF-3D93C9794155 Q28506946-F44AEA46-6833-40C1-8D19-65111368BEAD Q28510810-529460CB-38E0-4119-A36E-A154726BFF19 Q28593460-705CDC84-F3C9-4970-BF1E-FB4E740D1154 Q29614609-B3E1F432-6408-4311-B356-90B600FF1665 Q29617768-1DC6B96E-B493-448B-99B7-A2A3FDDB673A Q30353134-5DBA5FB4-8674-43C1-B5AF-5B75654F437C Q30994681-25E3AE16-FFB3-415D-BB14-A37C7705B155 Q33658452-C872A462-C421-47A5-9D18-07A1CE091C5A Q33831774-F689C895-6A32-4EDE-B0AA-59D5F5950063 Q33886976-17C47FAD-AD29-49C7-8F1A-2E39EFE46675 Q34029504-29302F3F-AF8E-4963-B52E-4EFC0B6F726B Q34075502-C34E0561-E4F4-471F-9344-72710B27A77F Q34140579-6D554B22-5F84-4A33-A1EC-DE10BEF8CA34 Q34189409-F120598C-9C26-4E7E-831B-F768E6E14B0B Q34241814-7B770D5B-A1EB-4DF5-A08B-C85824892A7F Q34330221-FEADA201-27F7-431C-A82C-C5FC2652B58A

P2860

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

http://www.wikidata.org/entity/Q24292161

description

2002 nî lūn-bûn

@nan

2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年学术文章

@wuu

2002年学术文章

@zh-cn

2002年学术文章

@zh-hans

2002年学术文章

@zh-my

2002年学术文章

@zh-sg

2002年學術文章

@yue

name

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@ast

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en-gb

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@nl

type

label

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@ast

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en-gb

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@nl

prefLabel

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@ast

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en-gb

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@nl

P1433

Q24292161-731FE705-1CDE-4BFC-BAD6-EFC79F88CEDD

P1476

Q24292161-1A08FF31-46A6-45F6-A886-E48A2D5998C8

P2093

Q24292161-0EA925C5-587E-4A25-B2BE-AD6B89D75AF3

Q24292161-0FB3994A-BD31-4E27-9CFF-A521172C2752

Q24292161-12B5D627-74A8-4BBA-9667-E570DB77953F

Q24292161-435A2809-DB19-4DA3-B51B-3CE4D037EC90

Q24292161-475EAB34-03FD-404B-914D-BFC606B0B60D

Q24292161-60202766-85E4-468F-98E9-9CFC73B3E6E6

Q24292161-79D75DF5-C400-4647-8185-E92D5A3C77F8

Q24292161-7A98C123-3373-4B52-8B21-1E6DA9AD8C1B

Q24292161-AD478A43-9A24-4FDE-A385-015A5B75CC0B

Q24292161-B659853B-ACDD-459E-95A4-C6514431CB81

P2860

Q24292161-106752D9-F1B4-4EB3-AA64-6FF7107DEC57

Q24292161-10ECB4E0-6859-47D0-A40C-6437C88B6ACA

Q24292161-178454F7-CDF9-4225-885F-D8FFDA85C185

Q24292161-3403BCBE-9822-470D-9380-7430FEC9466A

Q24292161-443BD9AF-F899-412C-82F2-D41B6540E29E

Q24292161-49A92C16-5769-4E2D-9C9A-E0DA08483A45

Q24292161-4A781B9E-DD73-4BC0-8B35-E8A9ED6A59EB

Q24292161-4A8B697C-5AD1-4EF5-96F5-325230A315C9

Q24292161-4B01E341-9857-4A56-A137-C851E0FA18F2

Q24292161-5AFAC80E-8555-4A1C-B775-5DC3DD6B92E2

P2888

Q24292161-BB64026D-433F-4653-9A83-F57728200CD9

P304

Q24292161-8EED767A-D7F0-443F-BFD6-FE43AC5D52BE

P31

Q24292161-DF1D0DD3-4FCB-4720-B0BA-7532C7C78D29

P3181

Q24292161-1A8CEBA6-DC32-4075-AE60-5A4BB5A6CE8B

P356

Q24292161-AC098A52-E955-4C6B-B83D-76DE3180EEDB

P407

Q24292161-9EC7CAD1-80DE-431B-9668-BB49CCC9B8BD

P433

Q24292161-775CE934-143A-4C39-A023-5232E07ED7E8

P478

Q24292161-B99AD098-59C5-4BF8-9643-98FF5CD7A889

P50

Q24292161-8495927A-7EC3-4A0F-A87E-0A1F20C0B708

Q24292161-AC17FED7-DACA-4F1C-ABC2-450C0CAD45C8

Q24292161-CCA3AFC0-33CB-45F5-B9A6-82B71ABDEC16

P577

Q24292161-191A2464-DB41-406E-97C5-81C9768754FB

P5875

Q24292161-92FE0FA4-6BDA-4EA7-886C-F5414A376518

P6179

Q24292161-BF3EE0B3-0DCD-433F-ACA6-661B148B1253

P698

Q24292161-7A2A2347-A463-4F0E-A512-042CDEDD62F2

P921

Q24292161-04F3BCFA-CECB-42BC-A6AB-AFA4FC69089E

Q24292161-33C7D799-232C-415A-9EDD-38B93328BC50

Q24292161-C47A5866-98E9-41C6-A6D0-7F5DC13CCBC5

Q24292161-CB2E82D4-76FA-45A3-9003-1411755354FE

Q24292161-F410371A-32B6-40D1-ADB2-038198A9C352

P3181

P356

P1433

Nature Cell Biology

P1476

Recruitment and activation of ...... ip-1 and a novel partner Hippi

@en

P2093

Abigail S Hackam

http://www.w3.org/2001/XMLSchema#string

Dita M Rasper

http://www.w3.org/2001/XMLSchema#string

Donald W Nicholson

http://www.w3.org/2001/XMLSchema#string

François G Gervais

http://www.w3.org/2001/XMLSchema#string

John P Vaillancourt

http://www.w3.org/2001/XMLSchema#string

John Tam

http://www.w3.org/2001/XMLSchema#string

Martina Metzler

http://www.w3.org/2001/XMLSchema#string

Roshni Singaraja

http://www.w3.org/2001/XMLSchema#string

Sophie Roy

http://www.w3.org/2001/XMLSchema#string

Steven Xanthoudakis

http://www.w3.org/2001/XMLSchema#string

P2860

Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

NMR structure and mutagenesis of the FADD (Mort1) death-effector domain

end3 and end4: two mutants defective in receptor-mediated and fluid-phase endocytosis in Saccharomyces cerevisiae.

The CARD domain: a new apoptotic signalling motif

Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

Sequence and domain structure of talin

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

P2888

P304

95-105

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

2313637

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NCB735

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

4

http://www.w3.org/2001/XMLSchema#string

P50

Claire-Anne Gutekunst

Michael R. Hayden

Blair R Leavitt

P577

2002-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

232782319

http://www.w3.org/2001/XMLSchema#string

P6179

1006024037

http://www.w3.org/2001/XMLSchema#string

P698

11788820

http://www.w3.org/2001/XMLSchema#string

P921

regulation of apoptotic process

Huntingtin interacting protein 1

Intraflagellar transport 57

Huntingtin interacting protein 1

Intraflagellar transport 57