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COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σRIG-G as a key mediator of the antiproliferative activity of interferon-related pathways through enhancing p21 and p27 proteinsCOP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulationDynamic regulation of the COP9 signalosome in response to DNA damageStabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasionCharacterization of the human COP9 signalosome complex using affinity purification and mass spectrometryThe DenA/DEN1 Interacting Phosphatase DipA Controls Septa Positioning and Phosphorylation-Dependent Stability of Cytoplasmatic DenA/DEN1 during Fungal DevelopmentCSNAP Is a Stoichiometric Subunit of the COP9 SignalosomeERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal Cancer DevelopmentIP-FCM measures physiologic protein-protein interactions modulated by signal transduction and small-molecule drug inhibitionThe novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancersALK1 signalling analysis identifies angiogenesis related genes and reveals disparity between TGF-beta and constitutively active receptor induced gene expressionIdentification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.Dual regulation of dendritic morphogenesis in Drosophila by the COP9 signalosome.COP9 subunits 4 and 5 target soluble guanylyl cyclase α1 and p53 in prostate cancer cells.Amplification of tumor hypoxic responses by macrophage migration inhibitory factor-dependent hypoxia-inducible factor stabilization.Loss of jab1 in osteochondral progenitor cells severely impairs embryonic limb development in mice.The COP9 signalosome subunit 6 (CSN6): a potential oncogeneJAB1/CSN5: a new player in cell cycle control and cancerCSN6 drives carcinogenesis by positively regulating Myc stability.Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers.Revisiting the COP9 signalosome as a transcriptional regulator.Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells.Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response MutantsRetinoblastoma protein regulation by the COP9 signalosome.Yeast as a tool to select inhibitors of the cullin deneddylating enzyme Csn5.Mapping the protein interaction network of the human COP9 signalosome complex using a label-free QTAX strategy.Regulating the stability and localization of CDK inhibitor p27(Kip1) via CSN6-COP1 axis.COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth.Expression of truncated Int6/eIF3e in mammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis.THE COP9 SIGNALOSOME, A NOVEL, ESSENTIAL REGULATOR OF SKELETAL DEVELOPMENT AND TUMORIGENESIS.Ubiquitin ligases in cancer: ushers for degradation.Macrophage migration inhibitory factor manipulation and evaluation in tumoral hypoxic adaptation.The coregulator AlienCSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progressionMechanisms of macrophage migration inhibitory factor (MIF)-dependent tumor microenvironmental adaptation.CSN5/JAB1 interacts with the centromeric components CENP-T and CENP-W and regulates their proteasome-mediated degradationModulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomasTargeted inhibition of the COP9 signalosome for treatment of cancerHigh-sensitivity detection and quantitative analysis of native protein-protein interactions and multiprotein complexes by flow cytometry.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The emerging role of the COP9 signalosome in cancer.
@ast
The emerging role of the COP9 signalosome in cancer.
@en
The emerging role of the COP9 signalosome in cancer.
@nl
type
label
The emerging role of the COP9 signalosome in cancer.
@ast
The emerging role of the COP9 signalosome in cancer.
@en
The emerging role of the COP9 signalosome in cancer.
@nl
prefLabel
The emerging role of the COP9 signalosome in cancer.
@ast
The emerging role of the COP9 signalosome in cancer.
@en
The emerging role of the COP9 signalosome in cancer.
@nl
P2860
P1476
The emerging role of the COP9 signalosome in cancer.
@en
P2093
Katharine S Richardson
Wayne Zundel
P2860
P304
P356
10.1158/1541-7786.MCR-05-0233
P577
2005-12-01T00:00:00Z