Targeted inhibition of the COP9 signalosome for treatment of cancer

Targeted inhibition of the COP9 signalosome for treatment of cancer

Item
http://www.wikidata.org/entity/Q37364323
Murine Myocardial Transcriptome Analysis Reveals a Critical Role of COPS8 in the Gene Expression of Cullin-RING Ligase Substrate Receptors and Redox and Vesicle Trafficking Pathways.SENP8 limits aberrant neddylation of NEDD8 pathway components to promote cullin-RING ubiquitin ligase functionFrontiers in Medicinal Chemistry 2017 in Bern, Switzerland.CSN5 Promotes Hepatocellular Carcinoma Progression by SCARA5 Inhibition Through Suppressing β-Catenin Ubiquitination.Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7.Prospect of divergent roles for the CUL3 system in vascular endothelial cell function and angiogenesis.Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.The COP9 signalosome inhibits Cullin-RING E3 ubiquitin ligases independently of its deneddylase activity.The COP9 Signalosome regulates seed germination by facilitating protein degradation of RGL2 and ABI5.Biology in Bloom: A Primer on the Arabidopsis thaliana Model System.Jab1/COPS5 as a Novel Biomarker for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Human Cancer.COP9 signalosome subunit CSN5, but not CSN6, is upregulated in lung adenocarcinoma and predicts poor prognosis.Interaction between parasite-encoded JAB1/CSN5 and macrophage migration inhibitory factor proteins attenuates its proinflammatory function.Computational Studies on the Inhibitor Selectivity of Human JAMM Deubiquitinylases Rpn11 and CSN5Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5
P2860

Targeted inhibition of the COP9 signalosome for treatment of cancer

Item
http://www.wikidata.org/entity/Q37364323
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 October 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Targeted inhibition of the COP9 signalosome for treatment of cancer
@en
Targeted inhibition of the COP9 signalosome for treatment of cancer.
@nl
type
label
Targeted inhibition of the COP9 signalosome for treatment of cancer
@en
Targeted inhibition of the COP9 signalosome for treatment of cancer.
@nl
prefLabel
Targeted inhibition of the COP9 signalosome for treatment of cancer
@en
Targeted inhibition of the COP9 signalosome for treatment of cancer.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P698
P932
P356
P1433
P1476
Targeted inhibition of the COP9 signalosome for treatment of cancer
@en
P2093
P2860
P2888
P304
P31
P356
P407
P478
P50
P577
P698
P932