c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation. - Test2 - elhamkhani - TriplyDB

c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.

c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.

http://www.wikidata.org/entity/Q34157660

about

Ubiquitylation-dependent downregulation of Nck regulates its functional activity Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling T cell activation E3 ubiquitin ligases and their control of T cell autoreactivity New Insights into How Trafficking Regulates T Cell Receptor Signaling Ubiquitylation as a Rheostat for TCR Signaling: From Targeted Approaches Toward Global Profiling Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases Signaling at neuro/immune synapses A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling Recruitment of the actin-binding protein HIP-55 to the immunological synapse regulates T cell receptor signaling and endocytosis PD-L1 co-stimulation contributes to ligand-induced T cell receptor down-modulation on CD8+ T cells RAS diseases in children The Cbl interactome and its functions Controlling NF-kappaB activation in T cells by costimulatory receptors Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection Whole-exome sequencing of a pedigree segregating asthma.Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster.Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells.Stoichiometry and intracellular fate of TRIM-containing TCR complexes.Role of c-Cbl-dependent regulation of phospholipase Cgamma1 activation in experimental choroidal neovascularization Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.Phospholipase C{gamma}1 is essential for T cell development, activation, and tolerance c-Cbl inhibition improves cardiac function and survival in response to myocardial ischemia Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.Organization of proximal signal initiation at the TCR:CD3 complex.Tonic ubiquitylation controls T-cell receptor:CD3 complex expression during T-cell development Manipulating antigenic ligand strength to selectively target myelin-reactive CD4+ T cells in EAE.Cbl enforces Vav1 dependence and a restricted pathway of T cell development Regulation of lck degradation and refractory state in CD8+ cytotoxic T lymphocytes Fast on-rates allow short dwell time ligands to activate T cells.E3 ubiquitin ligase Cbl-b in innate and adaptive immunity.T-cell regulation by casitas B-lineage lymphoma (Cblb) is a critical failsafe against autoimmune disease due to autoimmune regulator (Aire) deficiency.Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy

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c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.

http://www.wikidata.org/entity/Q34157660

description

2002 nî lūn-bûn

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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2002 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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name

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

@ast

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

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c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

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type

label

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

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c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

@en

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

@nl

prefLabel

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

@ast

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

@en

c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

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c-Cbl and Cbl-b regulate T cel ...... d-induced TCR down-modulation.

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Diana Haines

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Fang Huang

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Hemanta Kole

http://www.w3.org/2001/XMLSchema#string

Hua Gu

http://www.w3.org/2001/XMLSchema#string

Ihn-Kyung Jang

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Mayumi Naramura

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P2860

Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

Rab proteins as membrane organizers

Essential role of LAT in T cell development

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

T cell receptor signaling precedes immunological synapse formation

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met

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12

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3

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11050662

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1050575749

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12415267

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