The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.
about
The PICALM protein plays a key role in iron homeostasis and cell proliferationDecreased CALM expression reduces Aβ42 to total Aβ ratio through clathrin-mediated endocytosis of γ-secretaseClathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brainsSynaptic vesicle morphology: a case of protein sorting?Mice doubly-deficient in the Arf GAPs SMAP1 and SMAP2 exhibit embryonic lethalityPICALM modulates autophagy activity and tau accumulation.CALM regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells.The Biochemical Properties and Functions of CALM and AP180 in Clathrin Mediated Endocytosis.Cargo recognition in clathrin-mediated endocytosisA clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing.Effects of iron depletion on CALM-AF10 leukemias.Uncoupling the functions of CALM in VAMP sorting and clathrin-coated pit formation.Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.Turning CALM into excitement: AP180 and CALM in endocytosis and disease.The Role of PICALM in Alzheimer's Disease.Regulation of heme biosynthesis and transport in metazoa.Partial loss of CALM function reduces Aβ42 production and amyloid deposition in vivo.Loss of Dynamin 2 GTPase function results in microcytic anaemia.
P2860
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P2860
The clathrin assembly protein PICALM is required for erythroid maturation and transferrin internalization in mice.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The clathrin assembly protein ...... errin internalization in mice.
@ast
The clathrin assembly protein ...... errin internalization in mice.
@en
The clathrin assembly protein ...... errin internalization in mice.
@nl
type
label
The clathrin assembly protein ...... errin internalization in mice.
@ast
The clathrin assembly protein ...... errin internalization in mice.
@en
The clathrin assembly protein ...... errin internalization in mice.
@nl
prefLabel
The clathrin assembly protein ...... errin internalization in mice.
@ast
The clathrin assembly protein ...... errin internalization in mice.
@en
The clathrin assembly protein ...... errin internalization in mice.
@nl
P2093
P2860
P1433
P1476
The clathrin assembly protein ...... errin internalization in mice.
@en
P2093
Akira Tanimura
Hirokazu Tanaka
Itaru Matsumura
Kenji Tanabe
Kohji Takei
Mai Suzuki
Manabu Fukumoto
Natsuko Oe
Shinya Rai
Syunsuke Kon
P2860
P304
P356
10.1371/JOURNAL.PONE.0031854
P407
P577
2012-02-21T00:00:00Z