Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
about
Distinct initial SNARE configurations underlying the diversity of exocytosisFerlins: regulators of vesicle fusion for auditory neurotransmission, receptor trafficking and membrane repairNew insights into cochlear sound encodingQuantitation of the calcium and membrane binding properties of the C2 domains of dysferlinOtoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cellsIdentification of a novel pathogenic OTOF variant causative of nonsyndromic hearing loss with high frequency in the Ashkenazi Jewish population.A novel missense mutation in the C2C domain of otoferlin causes profound hearing impairment in an Omani family with auditory neuropathy.Synaptic transmission between end bulbs of Held and bushy cells in the cochlear nucleus of mice with a mutation in Otoferlin.Otoferlin deficiency in zebrafish results in defects in balance and hearing: rescue of the balance and hearing phenotype with full-length and truncated forms of mouse otoferlin.Relating structure and function of inner hair cell ribbon synapses.Developmental acquisition of a rapid calcium-regulated vesicle supply allows sustained high rates of exocytosis in auditory hair cells.Modes and regulation of endocytic membrane retrieval in mouse auditory hair cellsTransmitter release from cochlear hair cells is phase locked to cyclic stimuli of different intensities and frequencies.Short-term facilitation modulates size and timing of the synaptic response at the inner hair cell ribbon synapse.Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.Cholinergic efferent synaptic transmission regulates the maturation of auditory hair cell ribbon synapses.Calcium regulates molecular interactions of otoferlin with soluble NSF attachment protein receptor (SNARE) proteins required for hair cell exocytosis.Characterization of the lipid binding properties of Otoferlin reveals specific interactions between PI(4,5)P2 and the C2C and C2F domains.Myogenesis in dysferlin-deficient myoblasts is inhibited by an intrinsic inflammatory response.The SNARE complex in neuronal and sensory cells.Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.Comparative Transcriptome Analysis of Bombyx mori (Lepidoptera) Larval Midgut Response to BmNPV in Susceptible and Near-Isogenic Resistant Strains.Metabolic context regulates distinct hypothalamic transcriptional responses to antiaging interventionsPlasma Membrane Repair: A Central Process for Maintaining Cellular Homeostasis.Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1.Ca2+-Calmodulin regulates SNARE assembly and spontaneous neurotransmitter release via v-ATPase subunit V0a1.Structure and development of cochlear afferent innervation in mammals.Exocytosis and synaptic vesicle function.Synaptic plasticity in the auditory system: a review.The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis.Auditory neuropathy--neural and synaptic mechanisms.Function coupling of otoferlin with GAD65 acts to modulate GABAergic activity.Presynaptic pH and vesicle fusion in Drosophila larvae neurones.Dysferlin Binds SNAREs (Soluble N-Ethylmaleimide-sensitive Factor (NSF) Attachment Protein Receptors) and Stimulates Membrane Fusion in a Calcium-sensitive Manner.Muscle membrane repair and inflammatory attack in dysferlinopathy.Activity-Dependent Phosphorylation by CaMKIIδ Alters the Ca2+ Affinity of the Multi-C2-Domain Protein Otoferlin.Impaired muscle growth and response to insulin-like growth factor 1 in dysferlin-mediated muscular dystrophy.Hair Cell Transduction, Tuning, and Synaptic Transmission in the Mammalian Cochlea.The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.What's hot about otoferlin.
P2860
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P2860
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年學術文章
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Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@ast
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@en
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@nl
type
label
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@ast
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@en
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@nl
prefLabel
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@ast
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@en
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@nl
P2860
P356
P1476
Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
@en
P2860
P304
P356
10.1083/JCB.201002089
P407
P577
2010-10-01T00:00:00Z