Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans. - Test2 - elhamkhani - TriplyDB

Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.

Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.

http://www.wikidata.org/entity/Q34197008

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mTOR is a key modulator of ageing and age-related disease The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans The circadian clock coordinates ribosome biogenesis Integration of the unfolded protein and oxidative stress responses through SKN-1/Nrf Induction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathways Mechanisms of aging-related proteinopathies in Caenorhabditis elegans TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO Haploinsufficiency of akt1 prolongs the lifespan of mice Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control C. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan Extension A genome-wide screen of bacterial mutants that enhance dauer formation in C. elegans Detecting translational regulation by change point analysis of ribosome profiling data sets The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet LIN-35/Rb causes starvation-induced germ cell apoptosis via CED-9/Bcl2 downregulation in Caenorhabditis elegans.A cytoprotective perspective on longevity regulation Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome The general control nonderepressible-2 kinase mediates stress response and longevity induced by target of rapamycin inactivation in Caenorhabditis elegans AMPK at the nexus of energetics and aging.Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan.mTORC1/C2 and pan-HDAC inhibitors synergistically impair breast cancer growth by convergent AKT and polysome inhibiting mechanisms.The Mediator complex of Caenorhabditis elegans: insights into the developmental and physiological roles of a conserved transcriptional coregulator.Translational regulation in nutrigenomics.Drosophila RNA polymerase III repressor Maf1 controls body size and developmental timing by modulating tRNAiMet synthesis and systemic insulin signaling.Function and Regulation of Lipid Biology in Caenorhabditis elegans Aging.Proteomic Analysis of eIF5B Silencing-Modulated Proteostasis.Systems biology in aging: linking the old and the young.GCN-2 dependent inhibition of protein synthesis activates osmosensitive gene transcription via WNK and Ste20 kinase signaling.Pharmacological lifespan extension of invertebrates ω-6 Polyunsaturated fatty acids extend life span through the activation of autophagy.SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans.Role of oxygen consumption in hypoxia protection by translation factor depletion.eIF4B stimulates translation of long mRNAs with structured 5' UTRs and low closed-loop potential but weak dependence on eIF4G.Reduced insulin/insulin-like growth factor-1 signaling and dietary restriction inhibit translation but preserve muscle mass in Caenorhabditis elegans.Reducing translation through eIF4G/IFG-1 improves survival under ER stress that depends on heat shock factor HSF-1 in Caenorhabditis elegans.Interrelation between protein synthesis, proteostasis and life span Role of translation initiation factor 4G in lifespan regulation and age-related health Direct and indirect gene regulation by a life-extending FOXO protein in C. elegans: roles for GATA factors and lipid gene regulators.The search for evolutionary developmental origins of aging in zebrafish: a novel intersection of developmental and senescence biology in the zebrafish model system.Genome-scale studies of aging: challenges and opportunities

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Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.

http://www.wikidata.org/entity/Q34197008

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Life span extension via eIF4G ...... gene expression in C. elegans.

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J.CMET.2011.05.010

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Cell Metabolism

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Life span extension via eIF4G ...... gene expression in C. elegans.

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Alan Hubbard

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Aric N Rogers

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Bradford W Gibson

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Di Chen

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Gordon J Lithgow

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Gregg Czerwieniec

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Krysta Felkey

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Pankaj Kapahi

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Simon Melov

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The Mediator subunit MDT-15 confers metabolic adaptation to ingested material

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Ca2+ homeostasis in Brody's disease. A study in skeletal muscle and cultured muscle cells and the effects of dantrolene an verapamil

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Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression

Mutations in beta-spectrin disrupt axon outgrowth and sarcomere structure

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

DINAMelt web server for nucleic acid melting prediction.

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1

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21723504

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Caenorhabditis elegans

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