mTOR is a key modulator of ageing and age-related disease - Test2 - elhamkhani - TriplyDB

mTOR is a key modulator of ageing and age-related disease

mTOR is a key modulator of ageing and age-related disease

http://www.wikidata.org/entity/Q24610741

about

Age-associated bidirectional modulation of gene expression in single identified R15 neuron of Aplysia Unified theory of Alzheimer's disease (UTAD): implications for prevention and curative therapy Early injury of the neonatal lung contributes to premature lung aging: a hypothesis Unraveling the message: insights into comparative genomics of the naked mole-rat "Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 Diabetes Connecting the Dots: From DNA Damage and Repair to Aging Human longevity: Genetics or Lifestyle? It takes two to tango Developing criteria for evaluation of geroprotectors as a key stage toward translation to the clinic Molecular insights into the premature aging disease progeria Olive Oil and the Hallmarks of Aging Management of immunosuppressant agents following liver transplantation: Less is more The role of the ribosome in the regulation of longevity and lifespan extension Healthy aging: The ultimate preventative medicine Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation The neurology of mTOR Optimal body weight for health and longevity: bridging basic, clinical, and population research Autophagy and aging Radiation-Induced Bystander Response: Mechanism and Clinical Implications Mitochondrial proteostasis in the control of aging and longevity mTORC1 signaling activates NRF1 to increase cellular proteasome levels Nutritional regulation of stem and progenitor cells in Drosophila The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import Reduced expression of MYC increases longevity and enhances healthspan.Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.Independent and additive effects of glutamic acid and methionine on yeast longevity Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!Mechanisms of aging-related proteinopathies in Caenorhabditis elegans Cytoplasmic mRNA turnover and ageing Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake Quality control systems in cardiac aging Minireview: The Complexities of IGF/Insulin Signaling in Aging: Why Flies and Worms Are Not Humans The hallmarks of aging Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome Mitochondrial dysfunction in cardiac aging Differential Response of Human Embryonic Stem and Somatic Cells to Non-Cytotoxic Hydrogen Peroxide Exposure: An Attempt to Model In Vitro the Effects of Oxidative Stress on the Early Embryo Staying young at heart: autophagy and adaptation to cardiac aging Drug synergy drives conserved pathways to increase fission yeast lifespan

P2860

Q21266660-FD441BB1-1A19-4161-87FC-A821CAEE9F04 Q26382049-F230C282-F96B-4CEC-A28A-64F33B3F8318 Q26741052-3E5BDDDE-358C-4832-A74D-4C0346CC30BD Q26745908-D4975132-7BA4-4A66-8288-618257F208C5 Q26747251-91338EEF-E11C-43AD-9F03-528FFEFDCC70 Q26750854-5A699717-6DDF-43D0-8C86-F2F0773CCF28 Q26751013-722A0662-67F0-4EC3-89DF-C8AE10FDE871 Q26766217-4BC81707-CBE4-4809-ABE8-C0F1CA090A68 Q26768972-D087F60B-6435-4B78-9A25-DC83FBEEB46A Q26769864-9BE34E1A-4B90-4899-B1B2-44A97542BB85 Q26770033-D6C8B244-6507-459E-85EF-3149B5B67117 Q26770848-3D1CFB31-EF1C-427F-86DC-BCFD8F93A625 Q26770924-C66C0E87-35CF-4585-BE31-B0C16F254C04 Q26801523-C2F1E490-3B8C-48C5-BA5A-47B38CEB440A Q26824286-DB13486C-A5EB-4235-B9AE-DE18438C5EDD Q26828503-88BC994A-7E3F-461B-946F-55EEF572B6DD Q26853625-92D1EE25-1A02-4D13-A881-A8DE4CFEB91E Q26995531-5CB442AB-B552-4C04-B355-341A38C840A6 Q26999871-5190F65B-CD93-4AC4-A62B-EE212DFDCF3C Q27012468-1A297432-8CDF-453E-9669-594134A71CCD Q27026694-13B27FF0-580C-41CD-AFEE-D825F69C361A Q27027262-506C0602-7C5E-4AD0-B74F-4D5A75292B4C Q27311613-106A1E02-91F1-4F86-AC47-8033FE240099 Q27323151-1AA9A802-55F0-461B-8996-E21A6C2B1FC3 Q27342729-96ACD306-2B47-48BD-B9AA-EC52EC5889AB Q27937541-FB6EF55C-1179-4CEA-9FED-4FC584BE35E8 Q28068299-B27ABB14-1F73-4AFA-A8CC-2CD9EE0964D9 Q28077338-1F3572F6-F70B-4484-9667-29D2E9316008 Q28081605-5BE0474E-9C67-4EAF-94BF-7E3044C7C42A Q28083422-DF60BF91-BF41-4777-A3D8-0EE2176AA61B Q28084341-F1617B0E-FC56-45B1-A17D-8E0BCC63263C Q28085566-26E43C9D-4EAF-472A-9DE5-DD3282DEA535 Q28131641-FE78E8AD-FB71-4B4B-B14F-E4EE92EF12C5 Q28267272-E0F27797-831D-47DF-B33F-3F1EDC8A9447 Q28277112-25B3CA1A-57F8-4D4E-B816-98419DBCF82E Q28305597-D06B28BD-9961-49D0-A6F2-9D3FE5F2560D Q28389063-8ACABEEE-793A-4623-BCFF-728B4182CB1D Q28392180-966ABADC-74DD-42E6-92CF-0E4CB88EBD92 Q28393951-0EBBB263-B8E3-48AC-A9EA-382F41F0FCC3 Q28544630-9AE82AAF-3B1B-44A7-AEC7-31690DF0A85D

P2860

mTOR is a key modulator of ageing and age-related disease

http://www.wikidata.org/entity/Q24610741

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2013年の論文

@ja

2013年論文

@yue

2013年論文

@zh-hant

2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

name

mTOR is a key modulator of ageing and age-related disease

@ast

mTOR is a key modulator of ageing and age-related disease

@en

mTOR is a key modulator of ageing and age-related disease

@nl

type

label

mTOR is a key modulator of ageing and age-related disease

@ast

mTOR is a key modulator of ageing and age-related disease

@en

mTOR is a key modulator of ageing and age-related disease

@nl

prefLabel

mTOR is a key modulator of ageing and age-related disease

@ast

mTOR is a key modulator of ageing and age-related disease

@en

mTOR is a key modulator of ageing and age-related disease

@nl

P1433

Q24610741-D6BC2D97-C917-465B-A03C-AA34C9633833

P1476

Q24610741-2AE78EFD-A33F-42F3-9D22-A713A582069A

P2093

Q24610741-160917FF-56E2-46C1-B5A3-0A0F99CF8482

Q24610741-2E54265D-5179-4A84-8438-919A12F6002E

P2860

Q24610741-00D41A21-6C21-40CF-B5EC-AC5724FF8254

Q24610741-03C327AE-2027-455E-B147-6163F9A5109A

Q24610741-03F0DB2B-ACC0-4619-AC5F-EAEB4205E615

Q24610741-065B7446-A613-4E47-9E5F-D12A6D0D0954

Q24610741-0713B008-F963-4B1B-A951-C2DF96B686C2

Q24610741-0DCB056E-E835-41D1-AA25-3DD379547618

Q24610741-0F34F21D-32B1-41E2-946E-214B0ACA74BA

Q24610741-12930060-3CFB-42CB-B3F3-2ABE0241ED5C

Q24610741-190D39FD-C75C-4296-B79D-87E96C114EBC

Q24610741-1D77FAA8-4BA5-4DD1-90F5-13E1B000A842

P2888

Q24610741-0A495D63-08C7-4E1B-93DC-8C7DB19159C7

P304

Q24610741-37B2D961-54EF-4A0D-BBAB-4E94DA49A15C

P31

Q24610741-E6320E8D-D684-4483-AAD4-9D46719E223B

P3181

Q24610741-8BDE5FF3-1629-4350-B77A-466C27C20179

P356

Q24610741-9BACBBE4-BA30-4353-B532-97B0B8C096F9

P407

Q24610741-048702E9-FE43-437C-B060-1317EE3C7F5B

P433

Q24610741-BA89EA6D-100C-4CE0-A261-CAB7BCBDE9D8

P478

Q24610741-5438DE06-8D26-409E-B09F-4883BC2553B8

P50

Q24610741-47362856-4103-4223-BB73-B0C792F9210A

P577

Q24610741-9C84C62D-8A25-4C29-8E4B-18B140696DF2

P5875

Q24610741-C3A4B292-24DE-44F7-8954-10234860E554

P6179

Q24610741-D90E7585-A8AE-4069-8719-EA7C90E42DA1

P698

Q24610741-9D035B9D-B2C3-4179-AC70-821EC2EC0817

P921

Q24610741-79f9191b-4726-5b64-7a85-e88a5d2cd7e7

Q24610741-f9236f8b-4d0d-c213-d6ba-ddea8cdb4166

Q24610741-f9a4d8b2-4066-1803-784d-c2921af7f7a1

P932

Q24610741-14C56424-C026-421F-9BDE-39C8BABB2E85

P3181

P356

P1433

P1476

mTOR is a key modulator of ageing and age-related disease

@en

P2093

Peter S Rabinovitch

http://www.w3.org/2001/XMLSchema#string

Simon C Johnson

http://www.w3.org/2001/XMLSchema#string

P2860

Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease

Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Extension of chronological life span in yeast by decreased TOR pathway signaling

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

The TOR pathway comes of age

Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity

Extending healthy life span--from yeast to humans

Short-term calorie restriction enhances skeletal muscle stem cell function

P2888

P304

338-45

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

81789

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NATURE11861

http://www.w3.org/2001/XMLSchema#string

P407

P433

7432

http://www.w3.org/2001/XMLSchema#string

P478

493

http://www.w3.org/2001/XMLSchema#string

P50

Matt Kaeberlein

P577

2013-01-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

234157792

http://www.w3.org/2001/XMLSchema#string

P6179

1019515245

http://www.w3.org/2001/XMLSchema#string

P698

23325216

http://www.w3.org/2001/XMLSchema#string

P921

aging-associated diseases

P932

3687363

http://www.w3.org/2001/XMLSchema#string