Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.
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The N-terminal domain of mammalian soluble epoxide hydrolase is a phosphataseCell-specific subcellular localization of soluble epoxide hydrolase in human tissuesPurification and specificity of a human microsomal epoxide hydrataseDiscovery of inhibitors of soluble epoxide hydrolase: a target with multiple potential therapeutic indicationsImpact of soluble epoxide hydrolase and epoxyeicosanoids on human healthDetoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolaseBinding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activationThe role of long chain fatty acids and their epoxide metabolites in nociceptive signalingBacterial and fungal oxidation of dibenzofuranThiophene analogues of the carcinogens benzidine and 4-aminobiphenyl: evaluation in vitroEpoxidation of the stilbene double bond, a major pathway in aminostilbene metabolismHepatic and extrahepatic metabolism of 14C-styrene oxideDevelopment of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studiesThe 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic painAttenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitorPutative EPHX1 enzyme activity is related with risk of lung and upper aerodigestive tract cancers: a comprehensive meta-analysisDevelopment of a high-throughput screen for soluble epoxide hydrolase inhibitionBrassica napus soluble epoxide hydrolase (BNSEH1).Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies.Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate.EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides.Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression.Epoxides--is there a human health problem?Symmetric adamantyl-diureas as soluble epoxide hydrolase inhibitors.Polymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancerMerits and limitations of recombinant models for the study of human P450-mediated drug metabolism and toxicity: an intralaboratory comparison.History of drug metabolism research in Japan.Metabolic detoxification: implications for thresholds.Usefulness of genetic susceptibility and biomarkers for evaluation of environmental health risk.Quantitative assessment of the influence of EPHX1 gene polymorphisms and cancer risk: a meta-analysis with 94,213 subjects.Breast cancer: role of polymorphisms in biotransformation enzymes.Systematic review and meta-analysis of the relationship between EPHX1 polymorphisms and colorectal cancer riskEpoxide hydrolase activity in human skin.Kinetics and metabolism of clobazam in animals and man.Comparative biology of test species.Evaluation of a possible role for antimutagens, antiteratogens, and anticarcinogens in reducing environmental health hazards.Chemical structure, reactivity, and carcinogenicity of halohydrocarbonsOral toxicity of 1,1-dichloroethylene in the rat: effects of sex, age, and fastingMicrosomal epoxide hydrolase polymorphisms and lung cancer risk: a quantitative review.Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene
P2860
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P2860
Mammalian epoxide hydrases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds.
description
1973 nî lūn-bûn
@nan
1973 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1973 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1973年の論文
@ja
1973年学术文章
@wuu
1973年学术文章
@zh-cn
1973年学术文章
@zh-hans
1973年学术文章
@zh-my
1973年学术文章
@zh-sg
1973年學術文章
@yue
name
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@ast
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@en
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@nl
type
label
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@ast
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@en
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@nl
prefLabel
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@ast
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@en
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@nl
P2860
P1433
P1476
Mammalian epoxide hydrases: in ...... omatic and olefinic compounds.
@en
P2093
P2860
P304
P356
10.3109/00498257309151525
P407
P577
1973-05-01T00:00:00Z