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Stability-mediated epistasis constrains the evolution of an influenza proteinEvolution favors protein mutational robustness in sufficiently large populationsIn the light of directed evolution: pathways of adaptive protein evolutionFitness and its role in evolutionary geneticsDistribution of fitness effects among beneficial mutations before selection in experimental populations of bacteriaEvolution of sodium channels predates the origin of nervous systems in animalsHow are model protein structures distributed in sequence space?The distribution of fitness effects among beneficial mutationsOn the conservative nature of intragenic recombinationSearching sequence space by definably random mutagenesis: improving the catalytic potency of an enzymeAn algorithm for protein engineering: simulations of recursive ensemble mutagenesisThe genetic code constrains yet facilitates Darwinian evolutionExploring protein fitness landscapes by directed evolutionRobustness and evolvabilityCrystal structure of an ancient protein: evolution by conformational epistasisEvolution of biological complexityUnity and disunity in evolutionary sciences: process-based analogies open common research avenues for biology and linguistics.Rational Protein Engineering Guided by Deep Mutational ScanningThe analysis of clonal expansions in normal and autoimmune B cell repertoiresSynthetic peptide arrays for investigating protein interaction domainsViral quasispecies evolutionStructural plasticity of helical nanotubes based on coiled-coil assembliesAn epistatic ratchet constrains the direction of glucocorticoid receptor evolutionMetamorphic proteins mediate evolutionary transitions of structureRevisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residueFunctional significance of evolving protein sequence in dihydrofolate reductase from bacteria to humansMany Activities, One Structure: Functional Plasticity of Ribozyme FoldsE Pluribus Unum: 50 Years of Research, Millions of Viruses, and One Goal--Tailored Acceleration of AAV EvolutionProtein tolerance to random amino acid changeThermodynamics of neutral protein evolutionHow much of protein sequence space has been explored by life on Earth?Analyzing protein structure and function using ancestral gene reconstructionEvolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistanceNeurogenomics and the role of a large mutational target on rapid behavioral changeA New Take on John Maynard Smith's Concept of Protein Space for Understanding Molecular EvolutionContrasting effects of historical contingency on phenotypic and genomic trajectories during a two-step evolution experiment with bacteriaTradeoff between robustness and elaboration in carotenoid networks produces cycles of avian color diversificationContingency and entrenchment in protein evolution under purifying selectionDNA polymerases engineered by directed evolution to incorporate non-standard nucleotidesSpaces of the possible: universal Darwinism and the wall between technological and biological innovation
P2860
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P2860
description
1970 nî lūn-bûn
@nan
1970 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1970 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1970年の論文
@ja
1970年論文
@yue
1970年論文
@zh-hant
1970年論文
@zh-hk
1970年論文
@zh-mo
1970年論文
@zh-tw
1970年论文
@wuu
name
Natural selection and the concept of a protein space.
@ast
Natural selection and the concept of a protein space.
@en
Natural selection and the concept of a protein space.
@nl
type
label
Natural selection and the concept of a protein space.
@ast
Natural selection and the concept of a protein space.
@en
Natural selection and the concept of a protein space.
@nl
prefLabel
Natural selection and the concept of a protein space.
@ast
Natural selection and the concept of a protein space.
@en
Natural selection and the concept of a protein space.
@nl
P356
P1433
P1476
Natural selection and the concept of a protein space.
@en
P2093
P2888
P304
P356
10.1038/225563A0
P407
P577
1970-02-01T00:00:00Z
P6179
1021549008