Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.
about
Characterization of the human and mouse WRN 3'-->5' exonucleaseA functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNAWerner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activityWerner syndrome protein interacts functionally with translesion DNA polymerasesNucleolar localization of the Werner syndrome protein in human cellsThe spectrum of WRN mutations in Werner syndrome patientsDr. Carrel's immortal cellsA biomarker that identifies senescent human cells in culture and in aging skin in vivoMutator phenotype of Werner syndrome is characterized by extensive deletionsHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesPotential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function.The interaction site of Flap Endonuclease-1 with WRN helicase suggests a coordination of WRN and PCNAMacroautophagy and the oncogene-induced senescenceFunctional requirement of p23 and Hsp90 in telomerase complexesDeletion of Ku86 causes early onset of senescence in miceThe Werner's Syndrome RecQ helicase/exonuclease at the nexus of cancer and agingGenetic determinants of human health span and life span: progress and new opportunitiesMutations in the WRN gene in mice accelerate mortality in a p53-null backgroundCorrelation between deoxyribonucleic acid excision-repair and life-span in a number of mammalian speciesTelomere length predicts replicative capacity of human fibroblastsWerner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.Length-dependent degradation of single-stranded 3' ends by the Werner syndrome protein (WRN): implications for spatial orientation and coordinated 3' to 5' movement of its ATPase/helicase and exonuclease domainsIncreased gene expression of Alzheimer disease beta-amyloid precursor protein in senescent cultured fibroblasts.Some in-vitro comparisons of synovial cells dispersed by trypsin from rheumatoid and nonrheumatoid synovium.In vitro Therapeutic Effects of Low Level Laser at mRNA Level on the Release of Skin Growth Factors from Fibroblasts in Diabetic Mice.Acetylation of WRN protein regulates its stability by inhibiting ubiquitination.Observations on human amniotic fluid cell strains in serial culture.Osteosarcoma in a patient with Hutchinson-Gilford progeria.Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.Werner syndrome gene variants in human sarcomasReview of Two Siblings with Werner's Syndrome: A Case ReportStrand exchange of telomeric DNA catalyzed by the Werner syndrome protein (WRN) is specifically stimulated by TRF2One systemic administration of transforming growth factor-beta 1 reverses age- or glucocorticoid-impaired wound healingErythroid colony formation from human fetal liver.Colony size distributions as a measure of in vivo and in vitro aging.Identification of a coiled coil in werner syndrome protein that facilitates multimerization and promotes exonuclease processivityProgeria: a cell culture study on agingA role for SUV39H1-mediated H3K9 trimethylation in the control of genome stability and senescence in WI38 human diploid lung fibroblastsWI-38 senescence is associated with global and site-specific hypomethylation.
P2860
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P2860
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.
description
1970 nî lūn-bûn
@nan
1970 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1970 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1970年の論文
@ja
1970年論文
@yue
1970年論文
@zh-hant
1970年論文
@zh-hk
1970年論文
@zh-mo
1970年論文
@zh-tw
1970年论文
@wuu
name
Replicative life-span of culti ...... r's age, tissue, and genotype.
@ast
Replicative life-span of culti ...... r's age, tissue, and genotype.
@en
Replicative life-span of culti ...... r's age, tissue, and genotype.
@nl
type
label
Replicative life-span of culti ...... r's age, tissue, and genotype.
@ast
Replicative life-span of culti ...... r's age, tissue, and genotype.
@en
Replicative life-span of culti ...... r's age, tissue, and genotype.
@nl
prefLabel
Replicative life-span of culti ...... r's age, tissue, and genotype.
@ast
Replicative life-span of culti ...... r's age, tissue, and genotype.
@en
Replicative life-span of culti ...... r's age, tissue, and genotype.
@nl
P2093
P1476
Replicative life-span of culti ...... r's age, tissue, and genotype.
@en
P2093
P577
1970-07-01T00:00:00Z