A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
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GRM7 variants confer susceptibility to age-related hearing impairmentSelective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNSThe metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in ratsMolecular targets for antiepileptic drug developmentNeuroprotective and symptomatic effects of targeting group III mGlu receptors in neurodegenerative diseaseThe glutamatergic system as a target for neuropathic pain reliefMetabotropic Glutamate Receptor 7 (mGluR7) as a Target for the Treatment of Psychostimulant DependenceGroup III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviorsMetabotropic Glutamate Receptors 7 within the Nucleus Accumbens are Involved in Relief Learning in Rats.Identification of positive allosteric modulators VU0155094 (ML397) and VU0422288 (ML396) reveals new insights into the biology of metabotropic glutamate receptor 7Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behaviorAllosteric modulation of metabotropic glutamate receptors.Metabotropic glutamate receptors: from the workbench to the bedside.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsPreferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors.Targeting metabotropic glutamate receptors for novel treatments of schizophrenia.Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in ratsBitopic ligands: all-in-one orthosteric and allosteric.mGluR7's lucky number.Molecular Insights into Metabotropic Glutamate Receptor Allosteric ModulationMetabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism.Differential effects of mGluR7 and mGluR8 activation on pain-related synaptic activity in the amygdalaAllosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discoverymGluR7 genetics and alcohol: intersection yields clues for addiction.Deep brain stimulation, histone deacetylase inhibitors and glutamatergic drugs rescue resistance to fear extinction in a genetic mouse model.Functional monoclonal antibody acts as a biased agonist by inducing internalization of metabotropic glutamate receptor 7.Effects of metabotropic glutamate receptor ligands on male sexual behavior in rats.Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain.Are compounds acting at metabotropic glutamate receptors the answer to treating depression?Group III mGluR regulation of synaptic transmission at the SC-CA1 synapse is developmentally regulated.Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082.Metabotropic glutamate receptors mGluR4 and mGluR8 regulate transmission in the lateral olfactory tract-piriform cortex synapse.Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence.Synthesis and evaluation of [11C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain.The Emerging Role of Metabotropic Glutamate Receptors in the Pathophysiology of Chronic Stress-Related DisordersPractical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate ReceptorsHypothesis-driven medication discovery for the treatment of psychostimulant addictionGroup III metabotropic glutamate receptors (mGluRs) modulate transmission of gustatory inputs in the brain stem.Effects of a metabotropic glutamate receptor subtype 7 negative allosteric modulator in the periaqueductal grey on pain responses and rostral ventromedial medulla cell activity in rat.Allosteric modulators for mGlu receptors.
P2860
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P2860
A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A selective metabotropic gluta ...... tes stress parameters in vivo.
@ast
A selective metabotropic gluta ...... tes stress parameters in vivo.
@en
A selective metabotropic gluta ...... tes stress parameters in vivo.
@nl
type
label
A selective metabotropic gluta ...... tes stress parameters in vivo.
@ast
A selective metabotropic gluta ...... tes stress parameters in vivo.
@en
A selective metabotropic gluta ...... tes stress parameters in vivo.
@nl
prefLabel
A selective metabotropic gluta ...... tes stress parameters in vivo.
@ast
A selective metabotropic gluta ...... tes stress parameters in vivo.
@en
A selective metabotropic gluta ...... tes stress parameters in vivo.
@nl
P2093
P2860
P356
P1476
A selective metabotropic gluta ...... tes stress parameters in vivo.
@en
P2093
Cedric Mombereau
Herman van der Putten
Joachim Nozulak
Kayo Mitsukawa
Kevin H McAllister
Natacha Stoehr
Oliver Pescott
Peter J Flor
Rainer Kuhn
Rina Yamamoto
P2860
P304
18712-18717
P356
10.1073/PNAS.0508063102
P407
P577
2005-12-09T00:00:00Z