Engineering splicing factors with designed specificities
about
A universal code for RNA recognition by PUF proteinsEngineering RNA-binding proteins with diverse activitiesSpecific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding DomainsStacking interactions in PUF-RNA complexesAlternate Modes of Cognate RNA Recognition by Human PUMILIO ProteinsPatterns and plasticity in RNA-protein interactions enable recruitment of multiple proteins through a single siteAn artificial PPR scaffold for programmable RNA recognitionThe design and structural characterization of a synthetic pentatricopeptide repeat proteinApplications of Cas9 as an RNA-programmed RNA-binding proteinSR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymeraseMisregulation of Alternative Splicing in a Mouse Model of Rett SyndromeSynthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicingThe prospects for designer single-stranded RNA-binding proteins.The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration.The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression.Programmable RNA Tracking in Live Cells with CRISPR/Cas9.Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNAProbing RNA-protein networks: biochemistry meets genomicsTargeted translational regulation using the PUF protein family scaffold.A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells.Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins.Drosophila Pumilio protein contains multiple autonomous repression domains that regulate mRNAs independently of Nanos and brain tumorTranscriptome-wide identification and study of cancer-specific splicing events across multiple tumors.Divergence of Pumilio/fem-3 mRNA binding factor (PUF) protein specificity through variations in an RNA-binding pocketCooperativity in RNA-protein interactions: global analysis of RNA binding specificityHuman Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAsTarget selection by natural and redesigned PUF proteins.De-coding and re-coding RNA recognition by PUF and PPR repeat proteins.A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferationEngineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism.Drosophila Nanos acts as a molecular clamp that modulates the RNA-binding and repression activities of Pumilio.Pentatricopeptide repeats: modular blocks for building RNA-binding proteins.Modular recognition of nucleic acids by PUF, TALE and PPR proteins.Engineering RNA-binding proteins for biologyFinding the missing code of RNA recognition by PUF proteins.Synthetic biology devices and circuits for RNA-based 'smart vaccines': a propositional review.Engineering reprogrammable RNA-binding proteins for study and manipulation of the transcriptome.RNA-based gene circuits for cell regulation.A complex network of factors with overlapping affinities represses splicing through intronic elements.
P2860
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P2860
Engineering splicing factors with designed specificities
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Engineering splicing factors with designed specificities
@ast
Engineering splicing factors with designed specificities
@en
Engineering splicing factors with designed specificities
@nl
type
label
Engineering splicing factors with designed specificities
@ast
Engineering splicing factors with designed specificities
@en
Engineering splicing factors with designed specificities
@nl
prefLabel
Engineering splicing factors with designed specificities
@ast
Engineering splicing factors with designed specificities
@en
Engineering splicing factors with designed specificities
@nl
P2093
P2860
P356
P1433
P1476
Engineering splicing factors with designed specificities
@en
P2093
Cheom-Gil Cheong
Zefeng Wang
P2860
P2888
P304
P356
10.1038/NMETH.1379
P577
2009-10-04T00:00:00Z
P5875
P6179
1047504659