Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
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Role of LXRs in control of lipogenesisReduction of atherosclerosis in mice by inhibition of CD40 signallingKnockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotesOverexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesisA targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolismNormal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemiaSREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevationDeficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysisDietary Tributyrin Supplementation Attenuates Insulin Resistance and Abnormal Lipid Metabolism in Suckling Piglets with Intrauterine Growth RetardationSterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genesIncreased oxidative stress in obesity and its impact on metabolic syndromeHypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene deliveryOverexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearanceUnsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells.Lipid profile and serum characteristics of the blind subterranean mole rat, Spalax.Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease.Mammary gland expression of mouse mammary tumor virus is regulated by a novel element in the long terminal repeat.Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDLApolipoprotein E: from lipid transport to neurobiologyOther ways to skin a cat: activating SREBP without Scap.Activating signal cointegrator 2 required for liver lipid metabolism mediated by liver X receptors in mice.From diet to DNA: dietary patterning of gene expression.Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophyThe two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemiaThe familial hypercholesterolemia (FH)-North Karelia mutation of the low density lipoprotein receptor gene deletes seven nucleotides of exon 6 and is a common cause of FH in Finland.A dose-response study of the effects of dietary cholesterol on fasting and postprandial lipid and lipoprotein metabolism in healthy young men.Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid functionLiver, lipoproteins and disease: I. Biochemistry of lipoprotein metabolism.High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice.Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice.Recent developments in the treatment of atherosclerosis.Bio F1B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolismMaternal diet rich in saturated fats has deleterious effects on plasma lipids of mice.Transgenic mouse models of lipoprotein metabolism and atherosclerosisDiabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammationCholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver.Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia.Mesolimbic neuropeptide W coordinates stress responses under novel environments.
P2860
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P2860
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@ast
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@en
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@nl
type
label
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@ast
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@en
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@nl
prefLabel
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@ast
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@en
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@nl
P2093
P356
P1433
P1476
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors.
@en
P2093
J L Goldstein
R E Hammer
S Ishibashi
P304
P356
10.1126/SCIENCE.2244210
P407
P577
1990-11-01T00:00:00Z