Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression.
about
Calsequestrin 2 and arrhythmiasIn cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin bindingHierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathyKinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparksDysfunctional ryanodine receptors in the heart: new insights into complex cardiovascular diseasesCPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activityK201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulumMolecular evolution of the junctophilin gene familyCa(2+) signaling in the myocardium by (redox) regulation of PKA/CaMKIIThe ryanodine receptor leak: how a tattered receptor plunges the failing heart into crisisA network-oriented perspective on cardiac calcium signalingMinding the calcium store: Ryanodine receptor activation as a convergent mechanism of PCB toxicityRole of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunctionDissociation of FKBP12.6 from ryanodine receptor type 2 is regulated by cyclic ADP-ribose but not beta-adrenergic stimulation in mouse cardiomyocytesPhosphorylation of the cAMP-dependent protein kinase (PKA) regulatory subunit modulates PKA-AKAP interaction, substrate phosphorylation, and calcium signaling in cardiac cellsIn Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of -Adrenergic Receptor SignalingRole of CaMKIIdelta phosphorylation of the cardiac ryanodine receptor in the force frequency relationship and heart failureDisruption of protein kinase A localization using a trans-activator of transcription (TAT)-conjugated A-kinase-anchoring peptide reduces cardiac function.Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice.Axial tubule junctions control rapid calcium signaling in atriaIntermolecular failure of L-type Ca2+ channel and ryanodine receptor signaling in hypertrophy.Pivotal effects of phosphodiesterase inhibitors on myocyte contractility and viability in normal and ischemic hearts.Dysregulated sarcoplasmic reticulum calcium release: potential pharmacological target in cardiac disease.Role of RyR2 phosphorylation in heart failure and arrhythmias: Controversies around ryanodine receptor phosphorylation in cardiac disease.CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors.Role of RyR2 phosphorylation in heart failure and arrhythmias: protein kinase A-mediated hyperphosphorylation of the ryanodine receptor at serine 2808 does not alter cardiac contractility or cause heart failure and arrhythmiasTargeted ablation of cardiac sympathetic neurons reduces the susceptibility to ischemia-induced sustained ventricular tachycardia in conscious ratsCardiac ryanodine receptor phosphorylation: target sites and functional consequencesGenetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy.Mechanisms of Ca²+ handling in zebrafish ventricular myocytesβ-AR blockers suppresses ER stress in cardiac hypertrophy and heart failure.Impaired S-nitrosylation of the ryanodine receptor caused by xanthine oxidase activity contributes to calcium leak in heart failureCaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome.Pituitary adenylate cyclase activating polypeptide (PACAP) dilates cerebellar arteries through activation of large-conductance Ca(2+)-activated (BK) and ATP-sensitive (K ATP) K (+) channels.The ryanodine receptor in cardiac physiology and disease.Profile of Andrew R. Marks.ß-Adrenergic stimulation increases RyR2 activity via intracellular Ca2+ and Mg2+ regulationRyanodine receptors as pharmacological targets for heart disease.Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in miceEpac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart.
P2860
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P2860
Ryanodine receptor/calcium release channel PKA phosphorylation: a critical mediator of heart failure progression.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Ryanodine receptor/calcium rel ...... of heart failure progression.
@ast
Ryanodine receptor/calcium rel ...... of heart failure progression.
@en
Ryanodine receptor/calcium rel ...... of heart failure progression.
@nl
type
label
Ryanodine receptor/calcium rel ...... of heart failure progression.
@ast
Ryanodine receptor/calcium rel ...... of heart failure progression.
@en
Ryanodine receptor/calcium rel ...... of heart failure progression.
@nl
prefLabel
Ryanodine receptor/calcium rel ...... of heart failure progression.
@ast
Ryanodine receptor/calcium rel ...... of heart failure progression.
@en
Ryanodine receptor/calcium rel ...... of heart failure progression.
@nl
P2093
P2860
P356
P1476
Ryanodine receptor/calcium rel ...... of heart failure progression.
@en
P2093
Andrew R Marks
Anetta Wronska
John A Vest
Stephan E Lehnart
Steven Reiken
P2860
P304
P356
10.1073/PNAS.0510113103
P407
P577
2006-01-06T00:00:00Z