Making sense of G-quadruplex and i-motif functions in oncogene promoters. - Test2 - elhamkhani - TriplyDB

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

http://www.wikidata.org/entity/Q34271763

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Transcriptional stalling in B-lymphocytes: a mechanism for antibody diversification and maintenance of genomic integrity Solution structure of all parallel G-quadruplex formed by the oncogene RET promoter sequence A minimal i-motif stabilized by minor groove G:T:G:T tetrads Chromatin, DNA structure and alternative splicing G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptome Re-evaluation of G-quadruplex propensity with G4Hunter The oncogenic role of Yin Yang 1 General cell-binding activity of intramolecular G-quadruplexes with parallel structure TMPyP4, a Stabilizer of Nucleic Acid Secondary Structure, Is a Novel Acetylcholinesterase Inhibitor mRNA decay factor AUF1 maintains normal aging, telomere maintenance, and suppression of senescence by activation of telomerase transcription Topology of a G-quadruplex DNA formed by C9orf72 hexanucleotide repeats associated with ALS and FTD.Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences.Mechanistic insight into ligand binding to G-quadruplex DNA Identification of G-quadruplex structures that possess transcriptional regulating functions in the Dele and Cdc6 CpG islands.G-quadruplexes are specifically recognized and distinguished by selected designed ankyrin repeat proteins G-quadruplex nucleic acids and human disease Tertiary DNA structure in the single-stranded hTERT promoter fragment unfolds and refolds by parallel pathways via cooperative or sequential events.Bisquinolinium compounds induce quadruplex-specific transcriptome changes in HeLa S3 cell lines.Folding and hydrodynamics of a DNA i-motif from the c-MYC promoter determined by fluorescent cytidine analogs.Gaining insights into the small molecule targeting of the G-quadruplex in the c-MYC promoter using NMR and an allele-specific transcriptional assay.Intramolecular folding in human ILPR fragment with three C-rich repeats The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1.An in silico study of the differential effect of oxidation on two biologically relevant G-quadruplexes: possible implications in oncogene expression RHPS4 G-quadruplex ligand induces anti-proliferative effects in brain tumor cells.G-quadruplexes in viruses: function and potential therapeutic applications.Detection of cyclic diguanylate G-octaplex assembly and interaction with proteins Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex.Regulation of tyrosine hydroxylase transcription by hnRNP K and DNA secondary structure DNA acting like RNA.Formation of a unique cluster of G-quadruplex structures in the HIV-1 Nef coding region: implications for antiviral activity.Evaluation of fluorescent analogs of deoxycytidine for monitoring DNA transitions from duplex to functional structures Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease?APTE: identification of indirect read-out A-DNA promoter elements in genomes Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.Sites of instability in the human TCF3 (E2A) gene adopt G-quadruplex DNA structures in vitro Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1 Molecular classification, pathway addiction, and therapeutic targeting in diffuse large B cell lymphoma Biophysical Characterization of G-Quadruplex Recognition in the PITX1 mRNA by the Specificity Domain of the Helicase RHAU.Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH.

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Making sense of G-quadruplex and i-motif functions in oncogene promoters.

http://www.wikidata.org/entity/Q34271763

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@ast

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@en

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@nl

type

label

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@ast

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@en

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@nl

prefLabel

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@ast

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@en

Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@nl

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J.1742-4658.2010.07759.X

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Making sense of G-quadruplex and i-motif functions in oncogene promoters.

@en

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Laurence Hurley

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Samantha Kendrick

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Tracy A Brooks

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P2860

The Hallmarks of Cancer

Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis

Structure of an Unprecedented G-Quadruplex Scaffold in the Human c-kit Promoter

NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1

A G-Rich Sequence within the c-kit Oncogene Promoter Forms a Parallel G-Quadruplex Having Asymmetric G-Tetrad Dynamics

Altered gene expression in the Werner and Bloom syndromes is associated with sequences having G-quadruplex forming potential.

Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression

The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element

G-quadruplex nucleic acids and human disease

Unusual DNA structure of the diabetes susceptibility locus IDDM2 and its effect on transcription by the insulin promoter factor Pur-1/MAZ.

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3459-3469

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scholarly article

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10.1111/J.1742-4658.2010.07759.X

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17

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45423012

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20670278

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2971675

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