Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model - Test2 - elhamkhani - TriplyDB

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

http://www.wikidata.org/entity/Q34276376

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The endocannabinoid system in normal and pathological brain ageing Alterations in Mitochondrial Quality Control in Alzheimer's Disease Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease Diverse molecular targets for therapeutic strategies in Alzheimer's disease Shift in brain metabolism in late onset Alzheimer's disease: implications for biomarkers and therapeutic interventions Alzheimer's disease pathologic cascades: who comes first, what drives what Oxidized cholesterol as the driving force behind the development of Alzheimer's disease Mitochondrial permeability transition pore is a potential drug target for neurodegeneration Altered brain energetics induces mitochondrial fission arrest in Alzheimer's Disease.Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons HDAC6 inhibitor blocks amyloid beta-induced impairment of mitochondrial transport in hippocampal neurons Estrogen amelioration of Aβ-induced defects in mitochondria is mediated by mitochondrial signaling pathway involving ERβ, AKAP and Drp1.Targeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunities Automated detection of whole-cell mitochondrial motility and its dependence on cytoarchitectural integrity Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain Parkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brains Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic.Mitochondrial dysfunction and calcium deregulation by the RanBP9-cofilin pathway.Synaptic abnormalities in a Drosophila model of Alzheimer's disease Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers.Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple-Transgenic Alzheimer's Disease Mice.Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability.Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.Estrogen: a master regulator of bioenergetic systems in the brain and body Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases.Identification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction.Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.Cyclophilin D Promotes Brain Mitochondrial F1FO ATP Synthase Dysfunction in Aging Mice.Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease.Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity.Decreased proteolytic activity of the mitochondrial amyloid-β degrading enzyme, PreP peptidasome, in Alzheimer's disease brain mitochondria A mitochondrial etiology of Alzheimer and Parkinson disease Modulation of γ-secretase activity by multiple enzyme-substrate interactions: implications in pathogenesis of Alzheimer's disease Amyloid-β peptide binds to cytochrome C oxidase subunit 1.Targeting mitochondrial bioenergetics for Alzheimer's prevention and treatment.

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

http://www.wikidata.org/entity/Q34276376

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2010 nî lūn-bûn

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2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

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2010 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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type

label

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

@ast

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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prefLabel

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

@ast

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

@en

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model

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P2093

Alexander A Sosunov

http://www.w3.org/2001/XMLSchema#string

Guy M McKhann

http://www.w3.org/2001/XMLSchema#string

Heng Du

http://www.w3.org/2001/XMLSchema#string

Lan Guo

http://www.w3.org/2001/XMLSchema#string

Shiqiang Yan

http://www.w3.org/2001/XMLSchema#string

Shirley ShiDu Yan

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P2860

Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease

RAGE-mediated signaling contributes to intraneuronal transport of amyloid-beta and neuronal dysfunction

An intracellular protein that binds amyloid-beta peptide and mediates neurotoxicity in Alzheimer's disease

Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease

Abundant type 10 17 beta-hydroxysteroid dehydrogenase in the hippocampus of mouse Alzheimer's disease model

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Endophilin I expression is increased in the brains of Alzheimer disease patients

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

Interaction of amyloid binding alcohol dehydrogenase/Abeta mediates up-regulation of peroxiredoxin II in the brains of Alzheimer's disease patients and a transgenic Alzheimer's disease mouse model

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

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10.1073/PNAS.1006586107

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107

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2010-10-11T00:00:00Z

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47395691

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20937894

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Alzheimer's disease

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2972922

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