Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1. - Test2 - elhamkhani - TriplyDB

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

http://www.wikidata.org/entity/Q34293299

about

A key commitment step in erythropoiesis is synchronized with the cell cycle clock through mutual inhibition between PU.1 and S-phase progression Ineffective erythropoiesis and thalassemias Molecular basis of inherited microcytic anemia due to defects in iron acquisition or heme synthesis Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium Murine mutants in the study of systemic iron metabolism and its disorders: an update on recent advances Oxidative stress and the homeodynamics of iron metabolism β-thalassemias: paradigmatic diseases for scientific discoveries and development of innovative therapies Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5 Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis ISG15 modulates development of the erythroid lineage Future alternative therapies for β-thalassemia.Long-Term Dexamethasone Exposure Down-Regulates Hepatic TFR1 and Reduces Liver Iron Concentration in Rats β-Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis.Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities.Iron metabolism in thalassemia and sickle cell disease Survival and proliferative roles of erythropoietin beyond the erythroid lineage.Inflammation regulates TMPRSS6 expression via STAT5.Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism.Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways.The SH2B1 adaptor protein associates with a proximal region of the erythropoietin receptor.MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis.Erythropoietin critically regulates the terminal maturation of murine and human primitive erythroblasts.ID1 promotes expansion and survival of primary erythroid cells and is a target of JAK2V617F-STAT5 signaling Fixing frataxin: 'ironing out' the metabolic defect in Friedreich's ataxia Anemia, ineffective erythropoiesis, and hepcidin: interacting factors in abnormal iron metabolism leading to iron overload in β-thalassemia.The role of ineffective erythropoiesis in non-transfusion-dependent thalassemia.Gfi-1 inhibits proliferation and colony formation of p210BCR/ABL-expressing cells via transcriptional repression of STAT 5 and Mcl-1.Molecular regulation of cellular iron balance.Ineffective erythropoiesis and regulation of iron status in iron loading anaemias.Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.A Red Carpet for Iron Metabolism.The transferrin receptor: the cellular iron gate.Glucocorticoid causes iron accumulation in liver by up-regulating expression of iron regulatory protein 1 gene through GR and STAT5.beta-Thalassemia: HiJAKing Ineffective Erythropoiesis and Iron Overload Ferroportin and erythroid cells: an update.STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia.Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia.Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.

P2860

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P2860

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

http://www.wikidata.org/entity/Q34293299

description

2008 nî lūn-bûn

@nan

2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի օգոստոսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@ast

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@en

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@nl

type

label

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@ast

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@en

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@nl

prefLabel

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@ast

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@en

Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@nl

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BLOOD-2008-02-138339

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Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.

@en

P2093

Ernst W Müllner

http://www.w3.org/2001/XMLSchema#string

Hartmut Beug

http://www.w3.org/2001/XMLSchema#string

Helmuth Gehart

http://www.w3.org/2001/XMLSchema#string

Manfred Schifrer

http://www.w3.org/2001/XMLSchema#string

Marc A Kerenyi

http://www.w3.org/2001/XMLSchema#string

Matthias Artaker

http://www.w3.org/2001/XMLSchema#string

P2860

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

Interleukin-6 induces hepcidin expression through STAT3

All roads lead to ATF4

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA

Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Transferrin receptor is necessary for development of erythrocytes and the nervous system

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

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3878-3888

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scholarly article

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10.1182/BLOOD-2008-02-138339

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P433

9

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112

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Florian Grebien

Richard Moriggl

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2008-08-11T00:00:00Z

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23163625

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18694996

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2976851

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