Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia.
about
Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis.The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.Novel mechanisms of platelet clearance and thrombopoietin regulation.Inherited thrombocytopenia: novel insights into megakaryocyte maturation, proplatelet formation and platelet lifespan.Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance.The molecular regulation of Janus kinase (JAK) activationBCR-JAK2 drives a myeloproliferative neoplasm in transplanted mice.Regulating billions of blood platelets: glycans and beyond.Safety, tolerability, efficacy and pharmacodynamics of the selective JAK1 inhibitor GSK2586184 in patients with systemic lupus erythematosus.Overview of Transgenic Mouse Models of Myeloproliferative Neoplasms (MPNs).Glycans and the platelet life cycle.Myeloproliferative neoplasm stem cells.Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Filgotinib, a Selective JAK-1 Inhibitor, After Short-Term Treatment of Rheumatoid Arthritis: Results of Two Randomized Phase IIa Trials.Genetic Alterations of the Thrombopoietin/MPL/JAK2 Axis Impacting Megakaryopoiesis.Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation.H3K27 Methylation Dynamics during CD4 T Cell Activation: Regulation of JAK/STAT and IL12RB2 Expression by JMJD3.Report of the inaugural Interferon Research Summit: interferon in inflammatory diseases.
P2860
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P2860
Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Selective deletion of Jak2 in ...... l anemia and thrombocytopenia.
@en
Selective deletion of Jak2 in ...... l anemia and thrombocytopenia.
@nl
type
label
Selective deletion of Jak2 in ...... l anemia and thrombocytopenia.
@en
Selective deletion of Jak2 in ...... l anemia and thrombocytopenia.
@nl
prefLabel
Selective deletion of Jak2 in ...... l anemia and thrombocytopenia.
@en
Selective deletion of Jak2 in ...... l anemia and thrombocytopenia.
@nl
P2093
P2860
P1433
P1476
Selective deletion of Jak2 in ...... al anemia and thrombocytopenia
@en
P2093
Hui Hao-Shen
Jean Grisouard
Radek C Skoda
Stephan Dirnhofer
P2860
P356
10.3324/HAEMATOL.2013.100016
P50
P577
2014-02-07T00:00:00Z